DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14883 and GDPD2

DIOPT Version :9

Sequence 1:	NP_650547.1	Gene:	CG14883 / 41997	FlyBaseID:	FBgn0038432	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001164663.1	Gene:	GDPD2 / 54857	HGNCID:	25974	Length:	590	Species:	Homo sapiens

Alignment Length:	192	Identity:	44/192 - (22%)
Similarity:	70/192 - (36%)	Gaps:	55/192 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LTLLVVCIASKFVKLQRSPNEKRLLSLL---------------SSP------EEWPSYWPIANRA 88
            :.||...:|..|.::.|. ..|.||.||               |||      :..|....:.:|.
Human   168 IALLAWPVADTFYRIHRR-GPKILLLLLFFGVVLVIYLAPLCISSPCIMEPRDLPPKPGLVGHRG 231

  Fly    89 AGFDAPENSKAAIKK---CLAR-----------GYRNVLLDAGLTSCGEIVVANPTKINVAQ--- 136
            |...||||:..:::|   |.|.           |...::.|..|:....:....||:|....
Human   232 APMLAPENTLMSLRKTAECGATVFETDVMVSSDGVPFLMHDEHLSRTTNVASVFPTRITAHSSDF 296

  Fly   137 PLVELQKLN----ITEQHPM----------GSQYEAETVAPLRQLSDFLEAEAAETTVFLRL 184
            ...||::||    ..|:.|.          ..:.|::||..|.:|.:  ||.|...::...|
Human   297 SWTELKRLNAGSWFLERRPFWGAKPLAGPDQKEAESQTVPALEELLE--EAAALNLSIMFDL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14883	NP_650547.1	UgpQ	83..319	CDD:223657	30/133 (23%)
CG14883	NP_650547.1	PI-PLCc_GDPD_SF	84..320	CDD:301322	30/132 (23%)
GDPD2	NP_001164663.1	PI-PLCc_GDPD_SF	202..563	CDD:326331	34/157 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0584
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810