DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and Prss8

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_579929.1	Gene:	Prss8 / 76560	MGIID:	1923810	Length:	339	Species:	Mus musculus

Alignment Length:	280	Identity:	94/280 - (33%)
Similarity:	130/280 - (46%)	Gaps:	38/280 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IPFLLIAGILVI-LEASRTEAAVPRQPDSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNW 71
            :..||:.|:|.. :.|..|||:.......||..|..|..||:|:|:|:.....|:||.|::|:.|
Mouse    15 VTILLLLGLLQSGIRADGTEASCGAVIQPRITGGGSAKPGQWPWQVSITYDGNHVCGGSLVSNKW 79

  Fly    72 AITAAHCID-GHEQQPREFTLRQGSIMRTSGGT-VQPVKAIYKHPAYDRADMNFDVALLRTADGA 134
            .::||||.. .|.::..|..|....:...|..| |..|..|..|.:|.......|:||:|
Mouse    80 VVSAAHCFPREHSREAYEVKLGAHQLDSYSNDTVVHTVAQIITHSSYREEGSQGDIALIR----- 139

  Fly   135 LSLPL---GKVAPIRLPTVGEAISESMPAVVSGWGH------MSTSNPVLSSVLKSTTVLTVNQE 190
            ||.|:   ..:.||.||....:....:...|:||||      :.|..|     |:...|..:::|
Mouse   140 LSSPVTFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLQTPRP-----LQQLEVPLISRE 199

  Fly   191 KCHNDLRHHGGVTEA-------MFCA--AARNTDACQGDSGGPISA--QGT--LIGIVSWGVGCA 242
            .| :.|.:...|.|.       |.||  .....||||||||||:|.  :|.  |.||||||..|.
Mouse   200 TC-SCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPLSCPMEGIWYLAGIVSWGDACG 263

  Fly   243 DPYYPGVYTRLAHPTIRRWI 262
            .|..|||||..:  |...||
Mouse   264 APNRPGVYTLTS--TYASWI 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	84/249 (34%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	85/250 (34%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	85/250 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910