DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and prss27

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	281	Identity:	92/281 - (32%)
Similarity:	132/281 - (46%)	Gaps:	49/281 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLIAGILVILEASRTEAAVPRQPDSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITA 75
            ||:||..|  .|..|....|...| |||.|..|..|::|:|:|:..|..||||.|::||||.::|
Frog   397 LLLAGFAV--TAISTGCGQPAFSD-RIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSA 458

  Fly    76 AHCIDGHEQQPREFTLRQGSIM--------RTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTAD 132
            |||.      ||.:.:....::        .||...:..||.:..:|.|.....:.|:|::.
Frog   459 AHCF------PRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMVE--- 514

  Fly   133 GALSLPL---GKVAPIRLPTVGEAISESMPAVVSGWGH----MSTSNPVLSSVLKSTTVLTVNQE 190
              :..|:   ..:.||.:|...|.........|:|||:    :|.|.|.   .|:...|..||..
Frog   515 --MESPVTYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPY---PLQEVEVPLVNAS 574

  Fly   191 KCHNDLRHHGG--------VTEAMFCAA--ARNTDACQGDSGGPISAQG----TLIGIVSWGVGC 241
            .| :.:.|:..        |.:.|.||.  ....||||||||||::.:.    .|.||||||.||
Frog   575 SC-DTMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVSWGDGC 638

  Fly   242 ADPYYPGVYTRLAHPTIRRWI 262
            |.|..|||||:::  :...||
Frog   639 AQPNRPGVYTKVS--SFSSWI 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	81/254 (32%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	82/255 (32%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	82/255 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910