DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	86/245 - (35%)
Similarity:	134/245 - (54%)	Gaps:	24/245 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITAAHCIDGHEQQPREFTLRQGSIMRTS 100
            ::..|::|.||::|:|.||::..||.|||:::|::|.||||||. .....|:::.:..|.:: :.
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCF-VRSANPKDWKVSFGFLL-SK 248

  Fly   101 GGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSLPLGKVAPIRLPTVGEAISESMP---AVV 162
            ....:.||:|..|..|.....|.|:|::|     ||.|:.....||...:.||..:..|   .||
  Rat   249 PQAQRAVKSIVIHENYSYPAHNNDIAVVR-----LSSPVLYENNIRRACLPEATQKFPPNSDVVV 308

  Fly   163 SGWGHMST--SNPVLSSVLKSTTVLTVNQEKCHNDLRHHGGVTEAMFCAA--ARNTDACQGDSGG 223
            :|||.:.:  .:|   ::|:...|..::.:.|::...:.|.:|..|.||.  ....|||||||||
  Rat   309 TGWGTLKSDGDSP---NILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGG 370

  Fly   224 PISAQGT-----LIGIVSWGVGCADPYYPGVYTRLAHPTIRRWIRLLTKL 268
            |:.::.:     |.||||||..||.|..||||||:.|  .|.||...|.|
  Rat   371 PLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTH--YRDWISSKTGL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	82/237 (35%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	83/237 (35%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	82/237 (35%)
		Tryp_SPc	187..415	CDD:238113	84/239 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920