DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	263	Identity:	88/263 - (33%)
Similarity:	129/263 - (49%)	Gaps:	25/263 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ILVILEASRTEAAVPRQP--DSRIVNGREATEGQFPYQLSLR--RQTVHICGASILSSNWAITAA 76
            :|:.::.|.::..|..|.  ::|||.|..|:.|.:|:|:||.  :...|.||.|::||.|.:|||
Zfish    13 LLICVKGSLSQLNVCGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAA 77

  Fly    77 HCIDGHEQQPREFTLRQGSIMRTSGG-----TVQPVKAIYKHPAYDRADMNFDVALLRTADGALS 136
            ||:.|    ..|.||......||..|     |.:.|...:.|.:|:....:.|:||||.:.....
Zfish    78 HCLSG----VSETTLVVYLGRRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTF 138

  Fly   137 LPLGKVAPIRLPTVGEAISESMPAVVSGWGHMSTS-NPVLSSVLKSTTVLTVNQEKCHNDLRHHG 200
              ...:.|:.|.......|....:.::|||.:... |.....:|:.|.:..|..::| |.|...|
Zfish   139 --TNYIRPVCLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC-NALLGSG 200

  Fly   201 GVTEAMFCAAAR--NTDACQGDSGGPISAQGTLI----GIVSWGVGCADPYYPGVYTRLAHPTIR 259
            .||..|.||...  ..|.||||||||:..:...:    ||.|||.|||||..||||||::.  .:
Zfish   201 TVTNNMICAGLTQGGKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQ--YQ 263

  Fly   260 RWI 262
            .||
Zfish   264 SWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	82/239 (34%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	83/240 (35%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	83/240 (35%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900