DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and Prss53

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	282	Identity:	77/282 - (27%)
Similarity:	124/282 - (43%)	Gaps:	46/282 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PFLLIAGILVILEASRTEAAV-----PRQPDSRIVNGREATEGQFPYQLSLRRQTVHICGASILS 68
            |.|||.|.:|::|..:.....     |..|:.:..|   ...|::|:|.|:|||.||||..|:::
Mouse     7 PELLIVGAVVVIEGLQAAQRACGQRGPGPPEPQEGN---TLPGEWPWQASVRRQGVHICSGSLVA 68

  Fly    69 SNWAITAAHCIDG-HEQQPREFTLRQGSIM---RTSGGTVQPVKAIYKHPAYDRADMNFDVALLR 129
            ..|.:|||||.:. ...:...:::..||:.   ::.|.....|.|:....||:......|:|||:
Mouse    69 DTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQ 133

  Fly   130 ----TADGALSLPLGKVAPIRLPTVGEAISESMPAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQE 190
                |....|.||        .||.......|..|  :|| ..:||:  :|..|::..:..:::.
Mouse   134 LTHPTVQTTLCLP--------QPTYHFPFGASCWA--TGW-DQNTSD--VSRTLRNLRLRLISRP 185

  Fly   191 KC---HNDLRHH---GGVTEAMFCAAAR--NTDACQGDSGGPI-----SAQGTLIGIVSWGVGCA 242
            .|   :|.|...   ......|.|..|:  ....||||||||:     ......:||:|:...||
Mouse   186 TCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCA 250

  Fly   243 DPYYPGVYTRLA-HPTIRRWIR 263
            ....|.:.|.:| |.:   |::
Mouse   251 QEDTPVLLTDMAVHSS---WLQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	67/247 (27%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	68/247 (28%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		3/21 (14%)
		Tryp_SPc	45..271	CDD:238113	67/241 (28%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030