Protein Alignment CG10405 and F7

DIOPT Version :10

• Sequence 1: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 93/322 - (28%)
• Similarity: 135/322 - (41%)
• Gaps: 96/322 - (29%)

  Fly     2 QKCRAPIPFLLIA-------------GILVILEASRTEAAVPRQPDSRIVNGREATEGQFPYQLS 53
            :.||....:.|:|             |.:.|||.....     :|..|||.|:...:|:.|:|:.
Human   199 RSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNAS-----KPQGRIVGGKVCPKGECPWQVL 258

  Fly    54 LRRQTVHICGASILSSNWAITAAHCI---------------------DGHEQQPREFTLRQGSIM 97
            |......:||.:::::.|.::||||.                     ||.||..|
Human   259 LLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRR---------- 313

  Fly    98 RTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSLPL---GKVAPIRLPTVGEAISESMP 159
                     |..:.....|.....|.|:||||     |..|:   ..|.|:.||.  ...||...
Human   314 ---------VAQVIIPSTYVPGTTNHDIALLR-----LHQPVVLTDHVVPLCLPE--RTFSERTL 362

  Fly   160 A-----VVSGWGHM----STSNPVLSSVLKSTTVLTVNQEKCHNDLRHHG---GVTEAMFCA--A 210
            |     :|||||.:    :|:..::  ||....::|   :.|....|..|   .:||.||||  :
Human   363 AFVRFSLVSGWGQLLDRGATALELM--VLNVPRLMT---QDCLQQSRKVGDSPNITEYMFCAGYS 422

  Fly   211 ARNTDACQGDSGGPISA--QGT--LIGIVSWGVGCADPYYPGVYTRLAHPTIRRWIRLLTKL 268
            ..:.|:|:||||||.:.  :||  |.||||||.|||...:.|||||     :.::|..|.||
Human   423 DGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTR-----VSQYIEWLQKL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	80/267 (30%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	4/16 (25%)
		Tryp_SPc	242..478	CDD:238113	81/271 (30%)