Protein Alignment CG10405 and KLK11

DIOPT Version :10

• Sequence 1: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 71/254 - (27%)
• Similarity: 119/254 - (46%)
• Gaps: 45/254 - (17%)

  Fly    34 DSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITAAHCIDGHEQ--QPREFT------ 90
            ::||:.|.|......|:|.:|..:|..:|||::::..|.:|||||:.....  .|...:
Human    51 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSS 115

  Fly    91 -------------LRQGSIMRTSG-GTVQPVKAIYKHPAYDRA----DMNFDVALLRTADGALSL 137
                         |.|.::.:..| ...:.....:.||.::.:    |...|:.|::.|.
Human   116 NYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMAS----- 175

  Fly   138 PLG---KVAPIRLPTVGEAISESMPAVVSGWGHMSTSNPV--LSSVLKSTTVLTVNQEKCHNDLR 197
            |:.   .|.|:.|.:  ..::.....::||||  |||:|.  |...|:...:..:..:||.|  .
Human   176 PVSITWAVRPLTLSS--RCVTAGTSCLISGWG--STSSPQLRLPHTLRCANITIIEHQKCEN--A 234

  Fly   198 HHGGVTEAMFCAAAR--NTDACQGDSGGPISAQGTLIGIVSWGVG-CADPYYPGVYTRL 253
            :.|.:|:.|.||:.:  ..|:||||||||:....:|.||:|||.. ||....|||||::
Human   235 YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKV 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	71/252 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	71/252 (28%)