DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10405 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_001036717.1	Gene:	CG10405 / 41996	FlyBaseID:	FBgn0038431	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	260	Identity:	84/260 - (32%)
Similarity:	132/260 - (50%)	Gaps:	31/260 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EASRTEAAVPRQP-DSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITAAHCIDGHEQ 84
            :.:::..|..:.| :::||.|..|:.|.:|:|.||.....|.||.|::|..|.::||||...: .
Zfish    21 QPTQSPPACGKAPLNTKIVGGTNASAGSWPWQASLHESGSHFCGGSLISDQWILSAAHCFPSN-P 84

  Fly    85 QPREFTL---RQGSIMRTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSLPL---GKVA 143
            .|.::|:   ||...:.......:.|..:..||.|..:..:.|:|||.     ||.|:   ..:.
Zfish    85 NPSDYTVYLGRQSQDLPNPNEVSKSVSQVIVHPLYQGSTHDNDMALLH-----LSSPVTFSNYIQ 144

  Fly   144 PIRLPTVGEAI-SESMPAVVSGWGHMSTSNPVLS-SVLKSTTVLTVNQEKCHNDLRHHGG---VT 203
            |:.|...|... :::|  .::|||.:.:...:.| .:|:...|..|....| |.|  :||   :|
Zfish   145 PVCLAADGSTFYNDTM--WITGWGTIESGVSLPSPQILQEVNVPIVGNNLC-NCL--YGGGSSIT 204

  Fly   204 EAMFCAAAR--NTDACQGDSGGP--ISAQGTLI--GIVSWGVGCADPYYPGVYTRLAHPTIRRWI 262
            ..|.||...  ..|:||||||||  |.:..|.:  |:||:|.|||||.|||||.|::.  .:.||
Zfish   205 NNMMCAGLMQGGKDSCQGDSGGPMVIKSFNTWVQAGVVSFGKGCADPNYPGVYARVSQ--YQNWI 267

Fly 263 262
Zfish 268 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	80/242 (33%)
CG10405	NP_001036717.1	Tryp_SPc	37..263	CDD:238113	82/243 (34%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	80/242 (33%)
		Tryp_SPc	38..269	CDD:238113	82/243 (34%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810