DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and KIC1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_011970.1	Gene:	KIC1 / 856502	SGDID:	S000001144	Length:	1080	Species:	Saccharomyces cerevisiae

Alignment Length:	262	Identity:	91/262 - (34%)
Similarity:	147/262 - (56%)	Gaps:	7/262 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 DPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSK-DLILTEIRVLKDFNH-KNL 350
            |....:|.|:.:|:|..|:|:...:::.....|:|.:::.:.|.: :.:..||:.|..... .|:
Yeast    18 DVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNI 82

  Fly   351 VNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDI 415
            ..:..:||  .:..||::||:..||.|..::....:.|:.|..:.||.|.|:..:|...:|||||
Yeast    83 TRYYGSYL--KDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDI 145

  Fly   416 KSDNVLLGMDGSVKVTDFGFCANI-EGDEKRQTMVGTPYWMAPEVVTR-KKYGKKVDIWSIGIMA 478
            |:.|||:..:|:||:.|||..|.: :...:||||.||||||||||:.. ..|..||||||:||..
Yeast   146 KAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITT 210

  Fly   479 IEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHP 543
            .|:..|.|||.....|||:.||..:..|.::. ...|.:|::|:..||..:...|.:||:||...
Yeast   211 YEIATGNPPYCDVEALRAMQLIIKSKPPRLED-RSYSTSLKEFIALCLDEDPKERLSADDLLKSK 274

  Fly   544 FL 545
            |:
Yeast   275 FI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	90/260 (35%)
		S_TKc	293..545	CDD:214567	89/255 (35%)
KIC1	NP_011970.1	STKc_NAK1_like	21..295	CDD:270822	90/259 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910