Protein Alignment Pak3 and BCK1

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_012440.1
• Gene: BCK1 / 853350
• SGDID: S000003631
• Length: 1478
• Species: Saccharomyces cerevisiae
• Alignment Length: 628
• Identity: 154/628 - (24%)
• Similarity: 272/628 - (43%)
• Gaps: 150/628 - (23%)

  Fly    44 LPAPWVRLMNSQITRDEQDKNPDAAYHAVKYYNYSIKKKENEVFKPFITEDVI---------HEE 99
            :|.|: :..|..:.|.:.|::..:...::|     :|:|.|.......|.:.|         ...
Yeast   880 IPQPY-KGANDVMRRLKTDQDSTSTSPSLK-----MKQKVNRSNSTVSTSNSIFYSPSPLLKRGN 938

  Fly   100 SKEI-----------ENYVNYKNKHKSQDPEKSDDDGSS----------TATETESSSGCGSSAG 143
            ||.:           ||.:.:.:.....|.:.||||.||          ||.||.:.:.....:.
Yeast   939 SKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSD 1003

  Fly   144 NSNSSSINDSSQQSTVPLDALEEVFKELKT--NLEHRETLKAAPQ---------------EPP-- 189
            ||::.|               :|:|.:.:|  .:|.:.|.:.:|:               :.|
Yeast  1004 NSSTHS---------------DEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPIT 1053

  Fly   190 -----PVPPKK-----------SPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKINTDT 238
                 |..||.           |..|.|..|.....|..:.:|.: ..:.......||.|....|
Yeast  1054 EGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQ-DGLNGKNKPLNQAKTPKRT 1117

  Fly   239 IIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIY----VELR-----AICNSDDPRERYK 294
            ..|:...           .|..|.|....:.::.:.:::    ||:.     :|..:.:.:..||
Yeast  1118 KTIRTIA-----------HEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYK 1171

  Fly   295 -----TTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSK--------DLILTEIRVLKDFN 346
                 ..:.:|||:.|.|::..::.....:|||.:::...||:        :.:.:|:..|||.:
Yeast  1172 EFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLD 1236

  Fly   347 HKNLVNFLDAYLLEPEDQLW-VVMEYMDGGPLTDVV------TETVMKERQIACVCRETLYAISF 404
            |.|:|.:|.   .|.::.:: :.:||:.||.:..::      .|.::|.     :..:.|..:::
Yeast  1237 HLNIVQYLG---FENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKH-----LTTQVLKGLAY 1293

  Fly   405 LHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEG--DEKRQTMVGTPYWMAPEVV-TRKKYG 466
            ||:|||:|||:|:||:||..||..|::|||.....:.  .....||.||.:|||||:| |::.|.
Yeast  1294 LHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYS 1358

  Fly   467 KKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIA-ANGRPDIKSWDKL---SPNLQDFLDRCLQ 527
            .||||||:|.:.:||..|:.|:.....:.|::.|. :...|.|.. |.|   |...::|||.|.:
Yeast  1359 AKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPE-DTLPLISQIGRNFLDACFE 1422

  Fly   528 VEVDRRATADELLSHPFLNDCSEVKALVPNIKAAK--KVLRRN 568
            :..::|.||:|||||||    |||.... |.|:.:  |.::.|
Yeast  1423 INPEKRPTANELLSHPF----SEVNETF-NFKSTRLAKFIKSN 1460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	5/28 (18%)
		PKc_like	288..545	CDD:304357	90/283 (32%)
		S_TKc	293..545	CDD:214567	90/278 (32%)
BCK1	NP_012440.1	STKc_Bck1_like	1173..1440	CDD:270799	89/279 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910