Protein Alignment Pak3 and PBS2

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_012407.2
• Gene: PBS2 / 853313
• SGDID: S000003664
• Length: 668
• Species: Saccharomyces cerevisiae
• Alignment Length: 687
• Identity: 155/687 - (22%)
• Similarity: 250/687 - (36%)
• Gaps: 188/687 - (27%)

  Fly     8 KKKGGDGGSISEIGAPT-------NFQRHFHVSRNQETGDLEGLPAPWVRLMNSQITRDEQDKNP 65
            ::.|.|.||..:..:.|       |...|..|...||...|:       |..:....:.||||..
Yeast    23 EQTGSDNGSAVKRTSSTSSHYNNINADLHARVKAFQEQRALK-------RSASVGSNQSEQDKGS 80

  Fly    66 DAAYHAVKYYNYSIKKKENEVFKPF--------------ITEDVIHEESKE-IENYVNYKNKHKS 115
                      :.|.|..:..|.||.              ::..|:...||. ::|.::.:.....
Yeast    81 ----------SQSPKHIQQIVNKPLPPLPVAGSSKVSQRMSSQVVQASSKSTLKNVLDNQETQNI 135

  Fly   116 QDPEKSDDDGSSTATETESSSGCGS---SAGNSNSSSINDSSQQSTVPLDALEEVFKELKTNLEH 177
            .|...:.|....|||....::|..:   :...||::|....:|.              |..|
Yeast   136 TDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKAQL--------------LNPN--- 183

  Fly   178 RETLKAAPQEP----PPVPPKKSPHTIP-----PKPQIK-------PKPRVTQKF-SRTSDIRRD 225
                :.||:.|    .|..|..:||..|     ||..:.       |...::.|. ::|:...:.
Yeast   184 ----RRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRGLKLPPGGMSLKMPTKTAQQPQQ 244

  Fly   226 EDSDNQHKINTDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPR 290
            ......:|.:.:|:.....|    .|...||...|      ...|.|...        .:::.|.
Yeast   245 FAPSPSNKKHIETLSNSKVV----EGKRSNPGSLI------NGVQSTSTS--------SSTEGPH 291

  Fly   291 ERYKTTQEVG-------KGASGIVFIAA------DLQNES-------QVAVKTIDMKNQSSKDLI 335
            :...||...|       .|:||...:.|      |:::.|       .::.|.||..|.||..:.
Yeast   292 DTVGTTPRTGNSNNSSNSGSSGGGGLFANFSKYVDIKSGSLNFAGKLSLSSKGIDFSNGSSSRIT 356

  Fly   336 LTEIRVLKDFNHKN-----------------------------------------------LVNF 353
            |.|:..|.:..|.|                                               :|:|
Yeast   357 LDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDF 421

  Fly   354 LDAYLLEPEDQLWVVMEYMDGGPLTDVVTETV----MKERQIACVCRETLYAISFLHAK-GIIHR 413
            ..|:.:  |..:::.|||||||.|..:..|:.    :.|.|:|.:....::.:..|..: .||||
Yeast   422 YGAFFI--EGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHR 484

  Fly   414 DIKSDNVLLGMD-GSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVV-----TRKKYGKKVDIW 472
            |:|..|:|...: |:||:.|||...|:.. ...:|.:|...:||||.:     .|..|..:.|||
Yeast   485 DVKPTNILCSANQGTVKLCDFGVSGNLVA-SLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIW 548

  Fly   473 SIGIMAIEMIEGQ---PPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRA 534
            |:|:..:||..|:   ||..|:.....|..|.....|.:.| ||.|.:.|||:..|||...:||.
Yeast   549 SLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPS-DKFSSDAQDFVSLCLQKIPERRP 612

  Fly   535 TADELLSHPFL-----NDCSEVKALVPNIKAAKKVLR 566
            |...|..||:|     .|....:.:...::...|:||
Yeast   613 TYAALTEHPWLVKYRNQDVHMSEYITERLERRNKILR 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	12/60 (20%)
		PKc_like	288..545	CDD:304357	91/337 (27%)
		S_TKc	293..545	CDD:214567	90/332 (27%)
PBS2	NP_012407.2	PKc_PBS2_like	358..644	CDD:132953	76/289 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910