DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and SPS1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_010811.1	Gene:	SPS1 / 852135	SGDID:	S000002931	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	291	Identity:	93/291 - (31%)
Similarity:	152/291 - (52%)	Gaps:	21/291 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 PRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSK-DLILTEIRVLKDFNHKNLVN 352
            |.:.|.....:|:|..|.|:.|.|...:..||:|.:::::.... :|:..||..|.:.....:.|
Yeast    14 PSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITN 78

  Fly   353 FLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETV---MKERQIACVCRETLYAISFLHAKGIIHRD 414
            :: |.:|| :..:|:||||..||..:|::..:.   :.|.:::.:..|....:.:||.:..||||
Yeast    79 YI-ATMLE-DVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRD 141

  Fly   415 IKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRK--KYGKKVDIWSIGIM 477
            ||:.|:||..:|.||:.|||...:|....||.|.||||||||||||..:  .|.:|.||||:||.
Yeast   142 IKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGIT 206

  Fly   478 AIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSH 542
            ..|:::|.||.....|::.:..:.....|.::.  ..|...:||:..||......|.:|..|||.
Yeast   207 TYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQG--PFSDAAKDFVAGCLVKTPADRPSAYNLLSF 269

  Fly   543 PFLNDCSEVKALVPNIKA------AKKVLRR 567
            .|:.:.:     :.|:|:      .|||..|
Yeast   270 EFVKNIT-----ITNLKSDVDLIKQKKVQER 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	86/261 (33%)
		S_TKc	293..545	CDD:214567	85/257 (33%)
SPS1	NP_010811.1	STKc_MST3_like	16..291	CDD:270786	88/283 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910