DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pak3 and AT1G73660

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_177507.1	Gene:	AT1G73660 / 843701	AraportID:	AT1G73660	Length:	1030	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	122/551 - (22%)
Similarity:	227/551 - (41%)	Gaps:	98/551 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EGLPAPWVRLMN----SQITRDEQDKNPDAAYHAVKYYNYSIKKKENEVFKPFITEDVIHEESKE 102
            ||:.:|..:.|.    ||...|...:||..|...     :.:..:...|..|.:..:|.   .::
plant   495 EGVSSPAAQRMKVKDVSQYMIDAAKENPRLAQKL-----HDVLLESGVVAPPNLFSEVY---PQQ 551

  Fly   103 IENYVNYKN-----KHKSQDPEKSDD----DG--------------SSTATETESSSGCGSSAGN 144
            :|..|..||     |.:.:|.|.:.:    :|              |.|....:..:|...|..:
plant   552 LEATVESKNSTEAKKERGKDLETTQEGRHQNGFGPVRFLPPLPRVQSKTNAHDQRDNGKVVSQSD 616

  Fly   145 SNSSSINDSSQQSTVPLDALEEVFKELKTNLEHRETLKAAPQEPPPVP-PKKSPHTIPPKPQIKP 208
            |:.|..:.:....|||  |.......:.:::......|:|..:..|:. |..:..|......:..
plant   617 SSHSEASSTEYARTVP--AAVAAAAVVASSMVAAAAAKSANSDSSPIELPAAAAATATAAAVVAT 679

  Fly   209 KPRVTQKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDAGADDN---PD---ETILRRSKEK 267
            ...|:::....|:...|:.|.                |.:..|:.|:   |:   |.|..:|...
plant   680 AAAVSRQLELGSNSDGDDGSG----------------GHEPQGSGDSNHGPNSGGERISDKSIGN 728

  Fly   268 RAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTI---DMKNQ 329
            .:.|:|.:...:...:.      |.....:.:|.|:.|.|: ..|... ::||||..   |:..:
plant   729 ESSKSDCDDVSDCEILW------EEITVGERIGLGSYGEVY-RGDWHG-TEVAVKKFLDQDLTGE 785

  Fly   330 SSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVV--TETVMKERQIA 392
            :.:: ..:|:|::|...|.|:|.|:.|....|  .|.:|.|::..|.|..::  ....:.||:..
plant   786 ALEE-FRSEVRIMKKLRHPNIVLFMGAVTRPP--NLSIVTEFLPRGSLYRLIHRPNNQLDERRRL 847

  Fly   393 CVCRETLYAISFLHAKG--IIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMV------ 449
            .:..:....:::||:..  |:|||:||.|:|:..:..|||.|||.     ...|..|.:
plant   848 RMALDAARGMNYLHSCNPMIVHRDLKSPNLLVDKNWVVKVCDFGL-----SRMKHSTYLSSKSTA 907

  Fly   450 GTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANG----RPDIKS 510
            ||..||||||:..:...:|.|::|.|::..|:...|.|:....|::   ::.|.|    |.||.
plant   908 GTAEWMAPEVLRNEPADEKCDVYSYGVILWELFTLQQPWGKMNPMQ---VVGAVGFQHRRLDIP- 968

  Fly   511 WDKLSPNLQDFLDRCLQVEVDRRATADELLS 541
             |.:.|.:.|.:.:|.|.:...|.:..|:::
plant   969 -DFVDPAIADLISKCWQTDSKLRPSFAEIMA 998

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	10/34 (29%)
		PKc_like	288..545	CDD:304357	73/271 (27%)
		S_TKc	293..545	CDD:214567	72/266 (27%)
AT1G73660	NP_177507.1	EDR1	179..383	CDD:316869
AT1G73660	NP_177507.1	STKc_MAP3K-like	754..1000	CDD:270901	72/260 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910