DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and MKK9

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_177492.1	Gene:	MKK9 / 843685	AraportID:	AT1G73500	Length:	310	Species:	Arabidopsis thaliana

Alignment Length:	276	Identity:	80/276 - (28%)
Similarity:	128/276 - (46%)	Gaps:	47/276 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   299 VGKGASGIVFIAADLQNESQVAVKTI--DMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEP 361
            :|.|..|||:...........|:||:  ||....::.| :.|:.:|:..:...:|.....:....
plant    53 LGCGNGGIVYKVRHKTTSEIYALKTVNGDMDPIFTRQL-MREMEILRRTDSPYVVKCHGIFEKPV 116

  Fly   362 EDQLWVVMEYMDGGPLTDV---VTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLG 423
            ..::.::|||||||.|..:   ||     |:::|...::.|..:|:|||..|:|||||..|:||.
plant   117 VGEVSILMEYMDGGTLESLRGGVT-----EQKLAGFAKQILKGLSYLHALKIVHRDIKPANLLLN 176

  Fly   424 MDGSVKVTDFGFC-ANIEGDEKRQTMVGTPYWMAPEVVTRKKYGKKV-----DIWSIGIMAIEMI 482
            ....||:.|||.. ..:...:...:.|||..:|:||....:..|...     ||||.|:|.:|::
plant   177 SKNEVKIADFGVSKILVRSLDSCNSYVGTCAYMSPERFDSESSGGSSDIYAGDIWSFGLMMLELL 241

  Fly   483 EGQPPYLYETPLRALYLIAANGRPDIKSWDKL----------------SPNLQDFLDRCLQVEVD 531
            .|..|           |:....|||   |..|                |...:.|::.||:.:..
plant   242 VGHFP-----------LLPPGQRPD---WATLMCAVCFGEPPRAPEGCSEEFRSFVECCLRKDSS 292

  Fly   532 RRATADELLSHPFLND 547
            :|.||.:||:||||.:
plant   293 KRWTAPQLLAHPFLRE 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	78/272 (29%)
		S_TKc	293..545	CDD:214567	78/272 (29%)
MKK9	NP_177492.1	PKc_MAPKK_plant_like	46..308	CDD:132954	80/274 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910