DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pak3 and MAPKKK15

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001330365.1	Gene:	MAPKKK15 / 835600	AraportID:	AT5G55090	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	318	Identity:	93/318 - (29%)
Similarity:	157/318 - (49%)	Gaps:	25/318 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 YVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQ-VAVKTIDMKNQSSKDLILTEIR 340
            :|.|...|:.....:.:.....:|:|::..|.:.  :.|... .|||:.:.   ||...:..|..
plant    52 FVPLFFSCSVSMEEQNWIRGPIIGRGSTATVSLG--ITNSGDFFAVKSAEF---SSSAFLQREQS 111

  Fly   341 VLKDFNHKNLVNFLDAYLLEPEDQLW--VVMEYMDGGPLTDVVTET--VMKERQIACVCRETLYA 401
            :|...:...:|.::.:.:.:..|:|.  ::|||:.||.|.|::..:  .:.|..|....|:.|..
plant   112 ILSKLSSPYIVKYIGSNVTKENDKLMYNLLMEYVSGGSLHDLIKNSGGKLPEPLIRSYTRQILKG 176

  Fly   402 ISFLHAKGIIHRDIKSDNVLLGMDGSV-KVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRKKY 465
            :.:||.:||:|.|:||.||::|  |.: |:.|.|....:|.:|..: ..|||.:|:|||...::.
plant   177 LMYLHDQGIVHCDVKSQNVMIG--GEIAKIVDLGCAKTVEENENLE-FSGTPAFMSPEVARGEEQ 238

  Fly   466 GKKVDIWSIGIMAIEMIEGQPPY--LYETPLRALYLIAANGR-PDIKSWDKLSPNLQDFLDRCLQ 527
            ....|:|::|...|||..|..|:  |.:. :.|:|.|...|. |.|..|  ||...||||.:||:
plant   239 SFPADVWALGCTVIEMATGSSPWPELNDV-VAAIYKIGFTGESPVIPVW--LSEKGQDFLRKCLR 300

  Fly   528 VEVDRRATADELLSHPFL----NDCSEVKALVPNIKAAKKVLRRNVXLLCNHRTARLL 581
            .:..:|.|.:|||.||||    ||..:....: |..:...||.:....||....:|.:
plant   301 KDPKQRWTVEELLQHPFLDEEDNDSDQTGNCL-NSSSPSTVLDQRFWDLCETSRSRFI 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	80/265 (30%)
		S_TKc	293..545	CDD:214567	80/260 (31%)
MAPKKK15	NP_001330365.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910