DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and CPK1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_196107.1	Gene:	CPK1 / 830366	AraportID:	AT5G04870	Length:	610	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	118/480 - (24%)
Similarity:	198/480 - (41%)	Gaps:	107/480 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PEKSDDDGSSTATETESSSGCGSSAGNSNSSSINDSSQQSTVPL------------------DAL 164
            |...||..|.:..:..|.:..|......:....|...:|.|:|.                  :.|
plant    24 PRDGDDSASMSNGDIASEAVSGELRSRLSDEVQNKPPEQVTMPKPGTDVETKDREIRTESKPETL 88

  Fly   165 EEVFKELKTNLEHRETLKAAPQEPPPVPPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSD 229
            ||:..|.|...: :||......|..|.||.|     |.||  |...||:....||
plant    89 EEISLESKPETK-QETKSETKPESKPDPPAK-----PKKP--KHMKRVSSAGLRT---------- 135

  Fly   230 NQHKINTDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYK 294
                                        |::|:|..|                     :.:|.|.
plant   136 ----------------------------ESVLQRKTE---------------------NFKEFYS 151

  Fly   295 TTQEVGKGASGIVFIAADLQNESQVAVKTI-DMKNQSSKDL--ILTEIRVLKDF-NHKNLVNFLD 355
            ..:::|:|..|..|:..:.....:.|.|:| ..|..:.:|:  :..||:::... .|.|:::...
plant   152 LGRKLGQGQFGTTFLCVEKTTGKEFACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHPNVISIKG 216

  Fly   356 AYLLEPEDQLWV--VMEYMDGGPLTD-VVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKS 417
            ||    ||.:.|  |||...||.|.| ::......||:.|.:.|..:..:...|:.|::|||:|.
plant   217 AY----EDVVAVHLVMECCAGGELFDRIIQRGHYTERKAAELTRTIVGVVEACHSLGVMHRDLKP 277

  Fly   418 DNVLL---GMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAI 479
            :|.|.   ..|..:|..|||.....:.|:....:||:||::||||: ||:||.:.|:||.|::..
plant   278 ENFLFVSKHEDSLLKTIDFGLSMFFKPDDVFTDVVGSPYYVAPEVL-RKRYGPEADVWSAGVIVY 341

  Fly   480 EMIEGQPPYLYETPLRALYLIAANGRPDIKS--WDKLSPNLQDFLDRCLQVEVDRRATADELLSH 542
            .::.|.||:..||. :.::....:|..|..|  |..:|.:.:|.:.:.|..:..:|.||.::|.|
plant   342 ILLSGVPPFWAETE-QGIFEQVLHGDLDFSSDPWPSISESAKDLVRKMLVRDPKKRLTAHQVLCH 405

  Fly   543 PFLNDCSEVKALVPNIKAAKKVLRR 567
            |::    :|..:.|:......||.|
plant   406 PWV----QVDGVAPDKPLDSAVLSR 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	79/268 (29%)
		S_TKc	293..545	CDD:214567	78/263 (30%)
CPK1	NP_196107.1	STKc_CAMK	149..407	CDD:270687	77/263 (29%)
CPK1	NP_196107.1	PTZ00184	444..586	CDD:185504
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910