DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pak3 and AT3G45670

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_190153.1	Gene:	AT3G45670 / 823709	AraportID:	AT3G45670	Length:	379	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	96/382 - (25%)
Similarity:	163/382 - (42%)	Gaps:	62/382 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 IPPKPQIKPKPRVTQKFSR--------TSDIRRDEDSDNQHKINTDTI--IIKPAVGAQDAGADD 254
            |||.||   .|.:|.|.|.        :.:|::.:.:....|....:|  .::..:|.....|..
plant    18 IPPLPQ---NPILTVKLSPIILHVRRCSKNIKKKKRTRTPLKKKKKSISSSVESIIGVSFKSASQ 79

  Fly   255 NPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQN--ES 317
            ....|:.|....|:...     :|:.|.:                |:||.|.|::|....:  ::
plant    80 KHSTTVTRDGGVKKISS-----WVKSRLL----------------GEGAYGCVYLATSKDDIYKT 123

  Fly   318 QVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLE--PEDQLWVVMEYMDGGPLTDV 380
            :.|:|:.|:....|   ::.|.|:|:......::......:..  ...|..:::||..|..|.|:
plant   124 ERAIKSADVLKAWS---LMHEGRILRSLQSPFVIRCYGHEIAREGTGHQYNLILEYCSGQCLADM 185

  Fly   381 VTETV--MKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLG-------MDGSV-KVTDFGF 435
            :.:..  :.|..:.....:.|..:|::|.:.|||.:||.||:||.       .:|.: |:.|||.
plant   186 IEDNQGGIPEFDVKQFAIDVLSGLSYIHRRNIIHCEIKPDNLLLSPVDHRFRSNGFLTKIADFGL 250

  Fly   436 CANIEGDEK-----RQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLR 495
              ::|...|     |..|.||..:||||::........|||.:.|...:||:.|:..:.....|.
plant   251 --SMEKGSKEYGNGRGHMRGTTRYMAPELIGGGLLDFAVDICAFGCSVLEMLTGKRVWGEYGDLA 313

  Fly   496 ALYLIAANGRPDI--KSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSE 550
            ....:...|..|:  :...:||...||||.|||..|...|.|..||:.||||  ||:
plant   314 HDDWVDLIGHSDLTPQISIRLSAEAQDFLMRCLVKEPGSRWTIGELVDHPFL--CSD 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	73/277 (26%)
		S_TKc	293..545	CDD:214567	73/272 (27%)
AT3G45670	NP_190153.1	STKc_MAPKKK	96..365	CDD:270783	75/294 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910