DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and CPK16

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_179379.1	Gene:	CPK16 / 816299	AraportID:	AT2G17890	Length:	571	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	110/386 - (28%)
Similarity:	184/386 - (47%)	Gaps:	56/386 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 KSPHTIPPKPQIKPKP--------RVT-QKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDA 250
            ::||..||...:|.:|        .|| ||..||...|      |.....|.|....|....::.
plant    19 RNPHPHPPLTVVKSRPPRSPCSFMAVTIQKDHRTQPRR------NATAKKTPTRHTPPHGKVREK 77

  Fly   251 GADDNPDETILRRSKE-----KRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIA 310
            ...:|.     ||..|     ||.....|:            |...||...:.:|.|..|..::|
plant    78 VISNNG-----RRHGETIPYGKRVDFGYAK------------DFDHRYTIGKLLGHGQFGYTYVA 125

  Fly   311 ADLQNESQVAVKTIDMKNQS---SKDLILTEIRVLKDF-NHKNLVNFLDAYLLEPEDQLWVVMEY 371
            .|.:...:||||.||....:   :.:.:..|:::|:.. .|:|:|.|.:|:  |.::.:::|||.
plant   126 TDKKTGDRVAVKKIDKAKMTIPIAVEDVKREVKILQALTGHENVVRFYNAF--EDKNSVYIVMEL 188

  Fly   372 MDGGPLTDVV---TETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGM---DGSVKV 430
            .:||.|.|.:   .::...||..|.|.|:.|...:..|.:|::|||:|.:|.|...   |..:|.
plant   189 CEGGELLDRILARKDSRYSERDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEDSPLKA 253

  Fly   431 TDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLR 495
            ||||....|:..:|...:||:.|::||||:.|:. |.:.|:||||:::..::.|:.|:..:|. .
plant   254 TDFGLSDFIKPGKKFHDIVGSAYYVAPEVLKRRS-GPESDVWSIGVISYILLCGRRPFWDKTE-D 316

  Fly   496 ALYLIAANGRPDI--KSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFL---NDCSEV 551
            .::......:||.  |.|..:|.:.:||:.:.|..:...|.||.:.||||::   .|.||:
plant   317 GIFKEVLKNKPDFRRKPWPTISNSAKDFVKKLLVKDPRARLTAAQALSHPWVREGGDASEI 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	83/268 (31%)
		S_TKc	293..545	CDD:214567	81/263 (31%)
CPK16	NP_179379.1	STKc_CAMK	107..367	CDD:270687	81/263 (31%)
		S_TKc	108..368	CDD:214567	81/263 (31%)
		PTZ00184	404..549	CDD:185504
		EFh	415..476	CDD:238008
		EFh	496..550	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910