DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and oxsr1a

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001092217.1	Gene:	oxsr1a / 568602	ZFINID:	ZDB-GENE-070620-25	Length:	515	Species:	Danio rerio

Alignment Length:	321	Identity:	109/321 - (33%)
Similarity:	168/321 - (52%)	Gaps:	41/321 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 SDDP--------RERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDM-KNQSSKDLILTEIRV 341
            |:||        ::.|:..:.:|.||:.:|..|.....:.:||:|.|:: |.|:|.|.:|.||:.
Zfish     2 SEDPSSQPWSIDKDDYELQEVIGSGATAVVQAAYCKPRKEKVAIKRINLEKCQTSMDELLKEIQA 66

  Fly   342 LKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVV---------TETVMKERQIACVCRE 397
            :...:|.|:|::..::::  :|:||:||:.:.||.:.|.:         ...||.|..||.:.||
Zfish    67 MSQCHHPNIVSYYTSFVV--KDELWLVMKLLSGGSVLDFIKYIISKGEHKSGVMDEPSIATILRE 129

  Fly   398 TLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIE--GD----EKRQTMVGTPYWMA 456
            .|..:.:||..|.||||:|:.|:|||.||||::.|||..|.:.  ||    :.|:|.||||.|||
Zfish   130 VLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDMTRNKVRKTFVGTPCWMA 194

  Fly   457 PEVVTR-KKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRP-------DIKSWDK 513
            |||:.: :.|..|.|:||.||.|||:..|..||....|::.|.|...|..|       |.:...|
Zfish   195 PEVMEQVRGYDFKADLWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPCLETGVTDKEMVKK 259

  Fly   514 LSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKAL-------VPNIKAAKKVLRR 567
            ...:.:..:..|||.:.::|.||.|||.|.|.........|       .|.|....:.:||
Zfish   260 YGKSFRKMISLCLQKDPEKRPTAAELLKHKFFTKAKNTDYLKEKLLERAPTIGERSRKVRR 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	102/288 (35%)
		S_TKc	293..545	CDD:214567	100/275 (36%)
oxsr1a	NP_001092217.1	STKc_OSR1_SPAK	15..291	CDD:270787	100/277 (36%)
oxsr1a	NP_001092217.1	S_TKc	17..291	CDD:214567	100/275 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910