Protein Alignment Pak3 and pak6b

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001155959.1
• Gene: pak6b / 567874
• ZFINID: ZDB-GENE-041014-121
• Length: 607
• Species: Danio rerio
• Alignment Length: 645
• Identity: 201/645 - (31%)
• Similarity: 301/645 - (46%)
• Gaps: 135/645 - (20%)

  Fly    19 EIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLMNSQITRDEQDKNPDAAYHAVKYYNYSIKKKE 83
            ||..|.|||...|.|.:...|...|||..|..|:       |..|.|........:....::.::
Zfish    13 EISTPKNFQHRVHTSFDPVQGCFIGLPPQWQSLI-------ETLKRPKPVVDPSSFTQVQVRPQK 70

  Fly    84 NEVFKPFI-TEDVIHE----------------------------------ESKEIENY----VNY 109
            :.|...|| .||.|..                                  |..|.|.|    :|.
Zfish    71 SIVRGSFIGHEDYISAAIAQMSRLSVTSSNSLRRRSPSVRKRAQSLGRLGELAEAETYEYEELNN 135

  Fly   110 KNKHKSQDPEKSDDDGSSTATETESS-------------------------SGC--GSSAGNS-N 146
            .|...|.|..:......|..||:..|                         :||  ..:|||. |
Zfish   136 TNHRNSSDLHRGSRPIQSPQTESRQSPARARSVHEATMFTGLMPRDILLHRAGCEGTDNAGNKPN 200

  Fly   147 SSSINDSSQQSTVPLDALEEVFKELKTNLEHRETLKAAPQ-------EPPPVPPKKSPH-TIPPK 203
            ...::....||    |..:....:||...:.|      ||       ..|.:|....|: |..||
Zfish   201 QRPVSCLYSQS----DGAKLNSDQLKMETQRR------PQSTYDFKVNSPNLPAASKPNGTSSPK 255

  Fly   204 PQIKPKPRVTQKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDAGADDNPDETILRRSKEKR 268
            |........|.:.|.|         ||..|::|....:.|        |.|:|.|.   |.....
Zfish   256 PGHGIISMQTPRRSST---------DNTLKLSTIPADVPP--------AQDSPSEP---RQAPSG 300

  Fly   269 AQK--------TDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTID 325
            |..        |..:....|:.:.:..|||...:...::|:|::|:|.||.:..:..|||||.:|
Zfish   301 ASSPGLTEPSVTHTQFRAALQMVVDPGDPRSYLENFIKIGEGSTGVVCIAREKHSGRQVAVKMMD 365

  Fly   326 MKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQ 390
            ::.|..::|:..|:.:::|:.|:|:|....:.|:  .::|||:|||:.||.||::|:||.:.|.|
Zfish   366 LRKQQRRELLFNEVVIMRDYRHQNVVEMYKSALV--GEELWVIMEYLQGGALTNIVSETRLTEEQ 428

  Fly   391 IACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGD-EKRQTMVGTPYW 454
            ||.||...|.|:.:||::|:||||||||::||.:||.||::||||||.|..| .||:::||||||
Zfish   429 IATVCESVLQALCYLHSQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRRSLVGTPYW 493

  Fly   455 MAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQ 519
            ||||||::..||.:|||||:|||.:||::|:|||..|||:.|:..:.....|..::..|:||.|:
Zfish   494 MAPEVVSKTPYGTEVDIWSLGIMVVEMVDGEPPYFSETPISAMKRLRDEPPPTARNASKISPVLR 558

  Fly   520 DFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLRRNVXLLCNHRTAR 579
            ||||..|..|..:|::|.:||.||||..||..:.|:|.::..::            ||:|
Zfish   559 DFLDSMLTREPQQRSSASDLLQHPFLLQCSSPRCLIPLVEQTRR------------RTSR 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	17/53 (32%)
		PKc_like	288..545	CDD:304357	120/257 (47%)
		S_TKc	293..545	CDD:214567	117/252 (46%)
pak6b	NP_001155959.1	PBD	13..65	CDD:279166	17/58 (29%)
		STKc_PAK6	311..607	CDD:270821	131/310 (42%)
		S_TKc	338..584	CDD:214567	117/247 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820