DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and dapk3

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_690685.1	Gene:	dapk3 / 562194	ZFINID:	ZDB-GENE-030131-3026	Length:	453	Species:	Danio rerio

Alignment Length:	313	Identity:	83/313 - (26%)
Similarity:	149/313 - (47%)	Gaps:	47/313 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 QKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQS---- 330
            ::.|.|||               |...:|:|.|...||....:..:.::.|.|.|..:..|
Zfish     5 RQEDVEIY---------------YDMGEELGSGQFAIVRKCKEKSSGTEYAAKFIKKRRLSSSRR 54

  Fly   331 --SKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTE-TVMKERQIA 392
              |::.|..|:.:|::..|.|::...|  :.|.:..:.:::|.:.||.|.|.:.| ..:.|.:..
Zfish    55 GVSREEIEREVNILREIQHSNIITLHD--IFENKTDVILILELVSGGELFDFLAEKESLTEEEAT 117

  Fly   393 CVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSV-----KVTDFGFCANIEGDEKRQTMVGTP 452
            ...::.|..:.:||:|.|.|.|:|.:|::| :|.:|     |:.|||....|:...:.:.:.|||
Zfish   118 QFLKQILDGVHYLHSKRIAHFDLKPENIML-LDKNVPNPRIKLIDFGIAHQIKDGNEFKNIFGTP 181

  Fly   453 YWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAA-NGRPDIKSWDKLSP 516
            .::|||:|..:..|.:.|:||||::...::.|..|:|.||....|..|:| |...|.:.:...|.
Zfish   182 EFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSE 246

  Fly   517 NLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLRRNV 569
            ..:||:.|.|..:..:|.|.::.|.|.::                |.:.||||
Zfish   247 LAKDFIRRLLVKDPKKRMTIEDSLQHSWI----------------KVIKRRNV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	74/269 (28%)
		S_TKc	293..545	CDD:214567	74/264 (28%)
dapk3	XP_690685.1	STKc_DAPK	7..275	CDD:271007	78/285 (27%)
dapk3	XP_690685.1	S_TKc	13..275	CDD:214567	74/264 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910