DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and msn

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	108/284 - (38%)
Similarity:	159/284 - (55%)	Gaps:	19/284 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   278 VELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVL 342
            ::|.|:   .||...::..:.||.|..|.|:.....:.....|:|.:|:.....:::.| ||.||
  Fly    20 IDLTAL---KDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKL-EINVL 80

  Fly   343 KDF-NHKNLVNFLDAYLLE----PEDQLWVVMEYMDGGPLTDVVTET---VMKERQIACVCRETL 399
            |.: ||:|:..:..|::.:    .:||||:||||...|.:||:|..|   .:||..||.:|||.|
  Fly    81 KKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREIL 145

  Fly   400 YAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGD-EKRQTMVGTPYWMAPEVVTRK 463
            ..:|:||:..:||||||..||||..:..||:.|||..|.::.. .:|.|.:||||||||||:...
  Fly   146 RGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACD 210

  Fly   464 K-----YGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLD 523
            :     |..:.|:||:||.|:||.|.|||.....|:|||:||..|..|.:|| .|.|.....|:|
  Fly   211 ENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKS-KKWSKKFHGFID 274

  Fly   524 RCLQVEVDRRATADELLSHPFLND 547
            ..|..:..:|...:.||.|.|:.|
  Fly   275 TVLVKDYHQRPYTENLLKHGFIKD 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	104/270 (39%)
		S_TKc	293..545	CDD:214567	102/265 (38%)
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	104/275 (38%)
		S_TKc	32..296	CDD:214567	102/265 (38%)
		CNH	1183..1484	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010