DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and snrkb

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_957127.1	Gene:	snrkb / 393806	ZFINID:	ZDB-GENE-040426-1724	Length:	741	Species:	Danio rerio

Alignment Length:	269	Identity:	77/269 - (28%)
Similarity:	134/269 - (49%)	Gaps:	31/269 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 YKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDL----ILTEIRVLKDFNHKNLVNF 353
            |...:.:|||...:|.:|..:.....||||.||  .....||    :|.|:|.:|...|.|:|..
Zfish    16 YDLDRTLGKGHFAVVKLARHVFTGQLVAVKVID--KTKLDDLATGHLLQEVRCMKLVQHPNVVRL 78

  Fly   354 LDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRET--------LYAISFLHAKGI 410
            .:  :::.:.:|::::|..|||.:.|.:.      |....|..:|        :.||::.|...:
Zfish    79 YE--VIDTQTKLYLILELGDGGDMYDYIL------RHEGGVAEDTAKVHFAQIVRAIAYCHRLHV 135

  Fly   411 IHRDIKSDNVL-LGMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVVTRKKY-GKKVDIWS 473
            :|||:|.:||: ....|:||:|||||..:.:......|..|:..:.|||::..::| ...|||||
Zfish   136 VHRDLKPENVVFFRQQGTVKLTDFGFSNHFKPGTMLMTSCGSLAYSAPEILLGEEYDAPAVDIWS 200

  Fly   474 IGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSW--DKLSPNLQDFLDRCLQVEVDRRATA 536
            :|::...::.|.||:........|.:|.     |.:..  :.:|...:|.:.|.||.:..:||:.
Zfish   201 LGVILYMLVCGHPPFQETNDSETLIMIM-----DCRYTVPNHISAQCKDLISRMLQRDPAKRASL 260

  Fly   537 DELLSHPFL 545
            .|:.|||:|
Zfish   261 AEIESHPWL 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	76/267 (28%)
		S_TKc	293..545	CDD:214567	76/267 (28%)
snrkb	NP_957127.1	STKc_SNRK	12..269	CDD:270976	76/267 (28%)
		S_TKc	16..269	CDD:214567	76/267 (28%)
		UBA_SNRK	290..335	CDD:270524
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910