DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and Stk24

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_038949467.1	Gene:	Stk24 / 361092	RGDID:	1561742	Length:	443	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	106/278 - (38%)
Similarity:	158/278 - (56%)	Gaps:	18/278 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 DPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSK-DLILTEIRVLKDFNHKNLV 351
            ||.|.:...:::|||:.|.||...|.:.:..||:|.||::....: :.|..||.||...:...:.
  Rat    31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVT 95

  Fly   352 NFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIK 416
            .:..:||  .:.:||::|||:.||...|::....:.|.|||.:.||.|..:.:||::..||||||
  Rat    96 KYYGSYL--KDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIK 158

  Fly   417 SDNVLLGMDGSVKVTDFGFCANIEGDE-KRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIE 480
            :.||||...|.||:.|||....:...: ||.|.||||:||||||:.:..|..|.||||:||.|||
  Rat   159 AANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIE 223

  Fly   481 MIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFL 545
            :.:|:||:....|::.|:||..|..|.::.  ..|..|::|::.||..|...|.||.|||.|.|:
  Rat   224 LAKGEPPHSELHPMKVLFLIPKNNPPTLEG--SYSRPLKEFVEACLNKEPSFRPTAKELLKHKFI 286

  Fly   546 NDCSEVKALVPNIKAAKK 563
                        |:.|||
  Rat   287 ------------IRNAKK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	101/258 (39%)
		S_TKc	293..545	CDD:214567	98/253 (39%)
Stk24	XP_038949467.1	STKc_MST3_like	34..307	CDD:270786	104/275 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910