Protein Alignment Pak3 and max-2

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001300485.1
• Gene: max-2 / 3565400
• WormBaseID: WBGene00003144
• Length: 649
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 239/632 - (37%)
• Similarity: 347/632 - (54%)
• Gaps: 104/632 - (16%)

  Fly    16 SISEIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLM---NSQITRDEQDKNPDAAYHAVKYYNY 77
            |..:|..|.|.....||..:.:  ...|||.||:.::   .|..:..:|.|:|:|...|:|:|..
 Worm    37 SAMDISQPYNTVHRVHVGYDGQ--KFSGLPQPWMDILLRDISYFSLADQKKDPNAVVTALKFYAQ 99

  Fly    78 SIKKKE-------NEVFKPFITEDVIHEESKEIENYVNYKNKHKSQDPEKSDDDGSSTATETESS 135
            |:|:.|       |.||.....:||..:.:.::..::  :|...|        :||:|:..| |.
 Worm   100 SMKENEKTKFMTTNSVFTNSDDDDVDVQLTGQVTEHL--RNLQCS--------NGSATSPST-SV 153

  Fly   136 SGCGSSA-----GN---SNSSSINDS---SQQSTVPLDA---LEEVFKELKTNLEHRETLKAAPQ 186
            |...|||     ||   |.:||.:.|   |:::.||..|   ..|...:|||..  .||.|..|:
 Worm   154 SASSSSARPLTNGNNHLSTASSTDTSLSLSERNNVPSPAPVPYSESAPQLKTFT--GETPKLHPR 216

  Fly   187 EP----PPVPPKKS------------PHT---IPPK------PQIKPKPRVTQKFSRT------- 219
            .|    |||.|::|            |.|   .||.      |.:.|||...:..|.|
 Worm   217 SPFPPQPPVLPQRSKTASAVATTTTNPTTSNGAPPPVPGSKGPPVPPKPSHLKIASSTVSSGCSS 281

  Fly   220 --------------------SDIRRDEDSDNQHKINTDTIIIKPAVGAQDAGADDN--------P 256
                                |....|.|....:|.|::    ..:||.::.....|        |
 Worm   282 PQQYSSARSVGNSLSNGSVVSTTSSDGDVQLSNKENSN----DKSVGDKNGNTTTNKTTVEPPPP 342

  Fly   257 DETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAV 321
            :|..:|.....|.:.:|:|:..:||.|.|..:|..:|:..:::|.||||.||:|....:...|||
 Worm   343 EEPPVRVRASHREKLSDSEVLNQLREIVNPSNPLGKYEMKKQIGVGASGTVFVANVAGSTDVVAV 407

  Fly   322 KTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVM 386
            |.:..|.|..|:::||||:|:|.:.|.||||::::||::.:| |||||:|::||.|||||.:|.:
 Worm   408 KRMAFKTQPKKEMLLTEIKVMKQYRHPNLVNYIESYLVDADD-LWVVMDYLEGGNLTDVVVKTEL 471

  Fly   387 KERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMVGT 451
            .|.|||.|.:|.|.|:.|||...|:|||||||||||||:|.||:||.||||.|:...||.|:|||
 Worm   472 DEGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGT 536

  Fly   452 PYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSP 516
            ||||:||::.:|:|..||||||:||||:|||:|:||||.||||:|:||||.||:|:||..|:||.
 Worm   537 PYWMSPEILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLIAQNGKPEIKQRDRLSS 601

  Fly   517 NLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKK 563
            ...:|||:||.|:.|:||...|||:||||.....:.:|:|.|:|.::
 Worm   602 EFNNFLDKCLVVDPDQRADTTELLAHPFLKKAKPLSSLIPYIRAVRE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	16/56 (29%)
		PKc_like	288..545	CDD:304357	143/256 (56%)
		S_TKc	293..545	CDD:214567	142/251 (57%)
max-2	NP_001300485.1	STKc_PAK	378..631	CDD:270789	143/253 (57%)
		S_TKc	379..630	CDD:214567	142/251 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425477at33208
OrthoFinder	1	1.000	-	-		FOG0000763
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100484
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920