DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and Taok3

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001019425.1	Gene:	Taok3 / 304530	RGDID:	1562861	Length:	898	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	101/298 - (33%)
Similarity:	152/298 - (51%)	Gaps:	19/298 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 ELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDL---ILTEIR 340
            |:..:...:||.|.:....|:|.|:.|.|:.|.:......||:|.:....:.:.:.   ||.|:|
  Rat    10 EIAELFFKEDPEELFIDLHEIGHGSFGAVYFATNAHTNEVVAIKKMSYSGKQTHEKWQDILKEVR 74

  Fly   341 VLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDV--VTETVMKERQIACVCRETLYAIS 403
            .|:...|.|.:.:...||  .|...|:||||..|. .:|:  |.:..::|.:||.:....|..::
  Rat    75 FLQQLKHPNTIEYKGCYL--KEHTAWLVMEYCLGS-ASDLLEVHKKPLQEVEIAAITHGALQGLA 136

  Fly   404 FLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDEKRQTMVGTPYWMAPEVV---TRKKY 465
            :||...:||||||:.|:||...|.||:.|||..:..   ....:.|||||||||||:   ...:|
  Rat   137 YLHFHSLIHRDIKAGNILLTEPGQVKLADFGSASMA---SPANSFVGTPYWMAPEVILAMDEGQY 198

  Fly   466 GKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKS--WDKLSPNLQDFLDRCLQV 528
            ..||||||:||..||:.|.:||......:.|||.||.|..|.::|  |   :.:.:.|:|.||..
  Rat   199 DGKVDIWSLGITCIELAERKPPLFNMNAMSALYHIAQNDSPTLQSREW---TDSFRRFVDYCLHK 260

  Fly   529 EVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKVLR 566
            ....|..|.|||.|.|:......:.|:..|:..|..:|
  Rat   261 IPQERPAAAELLRHDFIRRERPPRVLIDLIQRTKDAVR 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	95/266 (36%)
		S_TKc	293..545	CDD:214567	92/261 (35%)
Taok3	NP_001019425.1	PKc_like	2..314	CDD:304357	101/298 (34%)
		S_TKc	24..277	CDD:214567	92/261 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..372
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..424
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	565..596
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910