Protein Alignment Pak3 and pak2a

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001002717.1
• Gene: pak2a / 266749
• ZFINID: ZDB-GENE-021011-2
• Length: 517
• Species: Danio rerio
• Alignment Length: 552
• Identity: 225/552 - (40%)
• Similarity: 306/552 - (55%)
• Gaps: 111/552 - (20%)

  Fly    19 EIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLM-NSQITRDEQDKNPDAAYHAVKYYNYSIKKK 82
            ||..|::|:...||..:..||:..|:|..|.||: .|.||:.||.|||.|....:|:|:.:...:
Zfish    74 EISNPSDFEHTIHVGFDSVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLKFYDSTGNSR 138

  Fly    83 ENEVFKPFITEDVIHEESKEIENYVNYKNKHKSQDPEKSDDDGSSTATETESSSGCGSSAGNSNS 147
            :.  :..|..:|.  .::|          |...|.|.|..||....|
Zfish   139 QK--YLSFTDKDA--PQAK----------KGSEQSPVKDPDDDDEDA------------------ 171

  Fly   148 SSINDSSQQSTVPLDALEEVFKELKTNLEHRETLKAAPQEPPPVPPKKSPHTIPPKPQIKPKPRV 212
                                                    ||||              :.|:|
Zfish   172 ----------------------------------------PPPV--------------VAPRP-- 180

  Fly   213 TQKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIY 277
                              ||.|:..|..:...:.|..|.||.:..:...::.|.| .:.||.||.
Zfish   181 ------------------QHTISVYTRSVIDPIPAPAAIADTDGSKAADKQKKGK-GKMTDEEIM 226

  Fly   278 VELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVL 342
            .:||.|.:..||:::|...:::|:||||.|:.|.|:....:||:|.|:::.|..|:||:.||.|:
Zfish   227 EKLRTIVSIGDPKKKYTRYEKIGQGASGTVYTAIDVATGQEVAIKQINLQKQPKKELIINEILVM 291

  Fly   343 KDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHA 407
            |:..:.|:|||||::|:  .|:|:|||||:.||.||||||||.|.|.|||.||||.|.|:.||||
Zfish   292 KELKNPNIVNFLDSFLV--GDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLHA 354

  Fly   408 KGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGDE-KRQTMVGTPYWMAPEVVTRKKYGKKVDI 471
            ..:|||||||||||||||||||:|||||||.|..:: ||.|||||||||||||||||.||.||||
Zfish   355 NQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDI 419

  Fly   472 WSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATA 536
            ||:|||||||:||:||||.|.|||||||||.||.|::::.:||||..:|||:|||:::|::|...
Zfish   420 WSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGGG 484

  Fly   537 DELLSHPFLNDCSEVKALVPNIKAAKKVLRRN 568
            .|||.||||.....:.:|.|.|.|||:.::.|
Zfish   485 KELLQHPFLKLAKPLSSLTPLILAAKEAMKSN 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	22/54 (41%)
		PKc_like	288..545	CDD:304357	159/257 (62%)
		S_TKc	293..545	CDD:214567	157/252 (62%)
pak2a	NP_001002717.1	PBD	74..129	CDD:279166	22/54 (41%)
		STKc_PAK2	222..517	CDD:132986	174/297 (59%)
		S_TKc	242..493	CDD:214567	157/252 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425477at33208
OrthoFinder	1	1.000	-	-		FOG0000763
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100484
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820