DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pak3 and sid1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_593564.1	Gene:	sid1 / 2542746	PomBaseID:	SPAC9G1.09	Length:	471	Species:	Schizosaccharomyces pombe

Alignment Length:	272	Identity:	100/272 - (36%)
Similarity:	157/272 - (57%)	Gaps:	17/272 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 YKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDL--ILTEIRVLKDFNHKNLVN--- 352
            |...:::|.|:.|:|:.|.:..:...:|:|.||::. ...|:  |..|:.:|.:.|..|::.
pombe     9 YTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLET-GIDDITDIEQEVFMLSNCNSSNVIQYYG 72

  Fly   353 -FLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIK 416
             |:|.|      .||::||:||||.::.::....:.|:.|:.:.||.||.:::||.:..||||||
pombe    73 CFVDGY------TLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIK 131

  Fly   417 SDNVLLGMD-GSVKVTDFGFCANI-EGDEKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAI 479
            :.|:||... |:||:.|||..|.: ....:|.|.||||:||||||:.:..||...||||:||.||
pombe   132 AANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAI 196

  Fly   480 EMIEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPF 544
            ||..|.||.....|:|.::.|..:..|.:.  |..||..:||:..||.:..:.|.:|.|||.|||
pombe   197 EMANGIPPRATMHPMRVIFEIPQSEPPKLD--DHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPF 259

  Fly   545 LNDCSEVKALVP 556
            :.....||.::|
pombe   260 IKSAGTVKDIIP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	96/259 (37%)
		S_TKc	293..545	CDD:214567	96/259 (37%)
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	100/272 (37%)
sid1	NP_593564.1	S_TKc	9..260	CDD:214567	96/259 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910