DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and nak1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_596023.1	Gene:	nak1 / 2539963	PomBaseID:	SPBC17F3.02	Length:	652	Species:	Schizosaccharomyces pombe

Alignment Length:	281	Identity:	99/281 - (35%)
Similarity:	153/281 - (54%)	Gaps:	15/281 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 YKTTQEVGKGASGIVFIAADLQNESQVAVKTIDM-KNQSSKDLILTEIRVLKDFNH---KNLVNF 353
            |...:.||:|:.|.|:.......:..||:|.::: .::.....|..|:.||.:...   :|::.:
pombe    10 YTKLELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKY 74

  Fly   354 LDAYLLEPEDQLWVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSD 418
            ..:||:  ...||::|:|..||.:..::....:.|..|:.:.||||.|:.|:|..||||||||:.
pombe    75 HGSYLV--GTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAA 137

  Fly   419 NVLLGMDGSVKVTDFGFCANIE-GDEKRQTMVGTPYWMAPEVV-TRKKYGKKVDIWSIGIMAIEM 481
            |:|:.|.|:||:.|||..|.:. ...||.|.:||||||||||: ..::|....||||:||.|.|:
pombe   138 NILVSMSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEI 202

  Fly   482 IEGQPPYLYETPLRALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLN 546
            ..|.||:..|.|.||:||||....|.:..  ..|..|::|:..|||....||..:.|||...|:.
pombe   203 ATGSPPHAKEDPFRAVYLIAHTAPPRLNG--NFSALLKEFIASCLQDVPQRRLDSSELLKSKFIK 265

  Fly   547 DCSEVKALVPNIKAAKKVLRR 567
            ..|.:     :|.....|::|
pombe   266 QYSRM-----SISELTNVVKR 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	94/257 (37%)
		S_TKc	293..545	CDD:214567	94/257 (37%)
nak1	NP_596023.1	PKc_like	8..282	CDD:304357	99/281 (35%)
nak1	NP_596023.1	S_TKc	10..264	CDD:214567	94/257 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910