Protein Alignment Pak3 and Pak5

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_006499571.1
• Gene: Pak5 / 241656
• MGIID: 1920334
• Length: 736
• Species: Mus musculus
• Alignment Length: 709
• Identity: 201/709 - (28%)
• Similarity: 304/709 - (42%)
• Gaps: 178/709 - (25%)

  Fly    19 EIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLM------------------------------- 52
            ||..|:||:...|...:.:.....|||..|..|:
Mouse    27 EISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGN 91

  Fly    53 ----------------NSQITRD-----EQDKNPD-----------------------------A 67
                            |..:||.     |....||                             |
Mouse    92 KSCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHSEENGFITFSQYSSESDTTA 156

  Fly    68 AY----------------------HAVKYYNYSIKKKENEVFKP-----------FITEDVIHEE 99
            .|                      ||.|...:::|.|..:.:.|           |..:...|.:
Mouse   157 DYTTEKYRDRSLYGDDLDLYYKSSHAAKQNGHAMKMKHGDAYYPEMKSLKTDLAGFPVDYHTHLD 221

  Fly   100 S-KEIENYVNYK-NKHKSQDPEKSDDDGSSTATETESSSGCG-SSAGNSNSS---SIND------ 152
            | ::...|.:.: :..::......|.....|.:.|..:|.|. .|...|.|.   |::|
Mouse   222 SLRKSSEYGDLRWDYQRASSSSPLDYSFQLTPSRTAGTSRCSKESLAYSESDWGPSLDDYDRRPK 286

  Fly   153 -SSQQSTVPLDALEEVFKELKTNLEH------RETLKAAPQ-------------EP----PPV-- 191
             |....|.|..|:.:..|. .:.|:.      ....|..||             ||    |.|
Mouse   287 SSYLHQTSPQPAMRQRSKS-GSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDY 350

  Fly   192 --------PPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHK--------INTDTII 240
                    ||.....|.|..|...|:.:....:|..|    .:.....||        :.|.:..
Mouse   351 DRAQMVFSPPLSGSDTYPRGPTKLPQSQSKAGYSSGS----HQYPSGYHKASLYHHPSLQTSSQY 411

  Fly   241 IKPA--VGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGA 303
            |..|  :.:....:...|..:....|.::.::.:..:....|:.:.:..||||......::|:|:
Mouse   412 ISTASYLSSLSISSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGS 476

  Fly   304 SGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVV 368
            :|||.||.:.....|||||.:|::.|..::|:..|:.:::|::|.|:|:..::||:  .|:||||
Mouse   477 TGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLV--GDELWVV 539

  Fly   369 MEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDF 433
            ||:::||.|||:||.|.|.|.|||.||...|.|:|:||.:|:||||||||::||..||.:|::||
Mouse   540 MEFLEGGALTDIVTHTRMNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDF 604

  Fly   434 GFCANIEGD-EKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRAL 497
            ||||.:..: .||:::|||||||||||::|..||.:|||||:|||.||||:|:|||..|.||:|:
Mouse   605 GFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAM 669

  Fly   498 YLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVP 556
            ..|..:..|.:|...|:|..|:.|||..|..|..:||||.|||.||||........:||
Mouse   670 RRIRDSLPPRVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVP 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	21/156 (13%)
		PKc_like	288..545	CDD:304357	129/257 (50%)
		S_TKc	293..545	CDD:214567	125/252 (50%)
Pak5	XP_006499571.1	CRIB_PAK_like	26..72	CDD:238526	11/44 (25%)
		STKc_PAK5	443..734	CDD:132989	134/288 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810