Protein Alignment Pak3 and pak-1

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001024377.1
• Gene: pak-1 / 180873
• WormBaseID: WBGene00003911
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 589
• Identity: 236/589 - (40%)
• Similarity: 337/589 - (57%)
• Gaps: 107/589 - (18%)

  Fly     7 FKKKGGDGGSISE---IGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLM-NSQITRDEQDKNPDA 67
            |.||..|....||   |..|:||:...||..:.:||:..|:|..|.||: :|||::.||.:||.|
 Worm    51 FMKKNKDKKEASEKPVISRPSNFEHTIHVGYDPKTGEFTGMPEAWARLLTDSQISKQEQQQNPQA 115

  Fly    68 AYHAVKYY--------------------------NYSIKKKENEVFKPFITEDVIHEESKEIENY 106
            ...|:|||                          :|.:|.      :|:.|..:.:
 Worm   116 VLDALKYYTQGESSGQKWLQYDMMFIDDAPSRTPSYGLKP------QPYSTSSLPY--------- 165

  Fly   107 VNYKNKHKSQDPEKSDDDGSSTATETESSSGCGSSAG-NSNSSSINDSSQQSTVPLDALEEVFKE 170
                :.:|.|||.|.:...:||     ||:|..|..| ...:.|:|::  :|::|
 Worm   166 ----HGNKIQDPRKMNPMTTST-----SSAGYNSKQGVPPTTFSVNEN--RSSMP---------- 209

  Fly   171 LKTNLEHRETLKAAPQEPPPVPPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKIN 235
                         ....|||||..::|..|.| |.|..:|      :||..| ..:..:.:.||.
 Worm   210 -------------PSYAPPPVPHGETPADIVP-PAIPDRP------ARTLSI-YTKPKEEEEKIP 253

  Fly   236 TDTIIIKPAVGAQDAGADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVG 300
            .   :.|...|.|..|          :::|:|   .||||:..:||.|.:..:|..:|:...::|
 Worm   254 D---LSKGQFGVQARG----------QKAKKK---MTDAEVLTKLRTIVSIGNPDRKYRKVDKIG 302

  Fly   301 KGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQL 365
            .||||.|:.|.::..|::||:|.:::|:|..|:||:.||.|:::..|.|:||:||:||:  .|:|
 Worm   303 SGASGSVYTAIEISTEAEVAIKQMNLKDQPKKELIINEILVMRENKHANIVNYLDSYLV--CDEL 365

  Fly   366 WVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKV 430
            ||||||:.||.|||||||..|::..||.||||.|.|:.|||::.:|||||||||:|||||||||:
 Worm   366 WVVMEYLAGGSLTDVVTECQMEDGIIAAVCREVLQALEFLHSRHVIHRDIKSDNILLGMDGSVKL 430

  Fly   431 TDFGFCANIEGDE-KRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPL 494
            |||||||.:..:: ||.|||||||||||||||||:||.|||:||:|||||||:||:||||.|.||
 Worm   431 TDFGFCAQLSPEQRKRTTMVGTPYWMAPEVVTRKQYGPKVDVWSLGIMAIEMVEGEPPYLNENPL 495

  Fly   495 RALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIK 559
            ||:||||.||:||....|.::...:||:|..|:|:|:.|.:|.:||:||||.....:.:|...|.
 Worm   496 RAIYLIATNGKPDFPGRDSMTLLFKDFVDSALEVQVENRWSASQLLTHPFLRCAKPLASLYYLIV 560

  Fly   560 AAKK 563
            ||||
 Worm   561 AAKK 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	23/57 (40%)
		PKc_like	288..545	CDD:304357	148/257 (58%)
		S_TKc	293..545	CDD:214567	147/252 (58%)
pak-1	NP_001024377.1	PBD	66..121	CDD:279166	22/54 (41%)
		PKc_like	287..547	CDD:304357	149/261 (57%)
		S_TKc	295..546	CDD:214567	147/252 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425477at33208
OrthoFinder	1	1.000	-	-		FOG0000763
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100484
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920