DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and strd-1

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	NP_001022902.1	Gene:	strd-1 / 176526	WormBaseID:	WBGene00013132	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	77/316 - (24%)
Similarity:	137/316 - (43%)	Gaps:	51/316 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 KRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQN-ESQVAVKTIDMKNQS 330
            |.|..|:||....|:        ...|...:.:|....|.:::..:.:. :..||:|...:.:..
Worm    34 KNATITEAEGVPNLK--------ETGYDCVRYMGTCNGGQIYLGRERKKLKDYVAIKKFAIDDVD 90

  Fly   331 SKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVVTETV---MKERQIA 392
            ....|..|...|:..:|.|::...:.::.  |..::.:...|:.|.|.|:|.|.:   :.|:..|
Worm    91 DYAAIAKESSNLRLMHHPNIIELCECFVY--ERSIYQITPAMNLGSLFDIVFEYMKWGINEKSAA 153

  Fly   393 CVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANI--------EGDEKRQTMV 449
            .:.|:.|.|:|:||.:..||||:|..::|:...|:||::.|.|...:        |.|...|..:
Worm   154 AITRQLLDALSYLHQRRYIHRDLKPKHILIDSSGNVKLSGFRFMIELNHHLDCVFEFDAHLQNQL 218

  Fly   450 GTPYWMAPEVVTRKKYG--KKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANG-------- 504
               |::||||:.:..:|  .|.||:.:||...|.|.|..|:....||..|:. ..||
Worm   219 ---YYLAPEVLAQNIHGYTSKSDIYMLGISICEAINGVMPFGELEPLEMLHR-KLNGQVPRPVDM 279

  Fly   505 ---------------RPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFL 545
                           ||......:.|..:.:|:..||..:..:|.:|.:|.|..:|
Worm   280 ISLKDDQKMGLDISHRPQEHLTRRFSKEMHEFIANCLDYDPQQRGSASDLKSSAWL 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	70/293 (24%)
		S_TKc	293..545	CDD:214567	70/288 (24%)
strd-1	NP_001022902.1	PKc_like	59..329	CDD:304357	67/275 (24%)
strd-1	NP_001022902.1	S_TKc	64..335	CDD:214567	68/276 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910