DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and AgaP_AGAP000747

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_003437088.1	Gene:	AgaP_AGAP000747 / 1272336	VectorBaseID:	AGAP000747	Length:	1499	Species:	Anopheles gambiae

Alignment Length:	341	Identity:	105/341 - (30%)
Similarity:	169/341 - (49%)	Gaps:	49/341 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 AQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKD 333
            |.:|.|:   ||:...:.||..:|..    :|||..|.|:.|.||..:.::|||.:..:|.....
Mosquito   619 AAETTAD---ELKYEYDLDDEGQRIL----LGKGTYGAVYAARDLTTQVKIAVKEVYERNTHDVQ 676

  Fly   334 LILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLW-VVMEYMDG-----------GPLTDVVTETVM 386
            .:..||::.....|:|:|.:..:   :.|:|.: :.||.:.|           |||.|
Mosquito   677 PLHEEIKLHSQLRHRNIVQYWGS---KSENQYFKIFMEQVPGGSLSALLSSKWGPLKD------- 731

  Fly   387 KERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLG-MDGSVKVTDFGFCANIEG-DEKRQTMV 449
            .|..||...|:.|..:.:||.:.|:|||||..|||:. ..|.||::|||....:.| :...:|..
Mosquito   732 SETTIAFYSRQILEGLKYLHDQKIVHRDIKGGNVLVNTYSGVVKISDFGTSKRLAGINPATETFT 796

  Fly   450 GTPYWMAPEVVTR--KKYGKKVDIWSIGIMAIEMIEGQPPYL-YETPLRALYLIA-ANGRPDIKS 510
            ||..:|||||:.:  :.||...||||.|...:||..|:||:: ...|..|::.:. ....|.|.
Mosquito   797 GTLQYMAPEVIDQGVRGYGPAADIWSFGCTVVEMATGKPPFVELGCPQAAMFKVGFYKTHPTIP- 860

  Fly   511 WDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKKV----------L 565
             ::||...::|:.||.:|.||:||||.|||..|||  |.:.|.:.|:..::..:          .
Mosquito   861 -EELSSMAKNFILRCFEVNVDKRATATELLEDPFL--CEKHKKMRPSFSSSSTISGLPHPGASEF 922

  Fly   566 RRNVXLLCNHRTARLL 581
            .|:|.:..:...::.|
Mosquito   923 SRSVSMPADRHNSKTL 938

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	91/274 (33%)
		S_TKc	293..545	CDD:214567	89/269 (33%)
AgaP_AGAP000747	XP_003437088.1	DUF4071	119..492	CDD:290020
		STKc_ASK	627..894	CDD:270794	93/282 (33%)
		S_TKc	641..894	CDD:214567	89/268 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910