Protein Alignment Pak3 and LOC100536197

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_003200338.1
• Gene: LOC100536197 / 100536197
• -ID: -
• Length: 693
• Species: Danio rerio
• Alignment Length: 723
• Identity: 195/723 - (26%)
• Similarity: 313/723 - (43%)
• Gaps: 190/723 - (26%)

  Fly     3 FTKWFKKKGGDGGSISEIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLMNSQITRDEQDKNPDA 67
            |.|..||:       .||.||.||:...|.|.:.:.|...|||..|..|:       |..:.|..
Zfish     2 FRKKKKKR-------PEISAPKNFEHRVHTSFDAKRGVFVGLPTQWQSLI-------ENLRRPKP 52

  Fly    68 AYHAVKYYNYSIKKKENEVFKPFITEDVIHEESKEIENYVNYKNKHKSQDPEKSDDDGSSTATET 132
            .....:.....:|.|:..|....|             .:.:|.:...|.....|....:|....:
Zfish    53 MVDPSRITPVELKPKKTIVRGSMI-------------GHGDYISAMLSDMSRLSVTSSNSLRKSS 104

  Fly   133 ESSSGCGSSAGN----SNSSSINDSSQQSTVPLDALEEVFKELKTN-----------LEHRETLK 182
            .|:.....|.|.    :.:.::.|..|..|  ||..|..:.|...|           |:...||:
Zfish   105 PSARKRAQSLGRLGELNEADALGDGYQYET--LDDPEPHWSERARNIHSASGTPYMGLKKSVTLQ 167

  Fly   183 ---------------------AAPQEP--PPVPPKKSPHTIPPKPQI------------------ 206
                                 ..|..|  ||.||...|...||:|..
Zfish   168 PNGILPRAKSTYEVSMSCLDGPLPPHPALPPPPPPPFPVPEPPRPLYLAGDIGSPTERLMMRREF 232

  Fly   207 ------KPKPRVTQKFSRTS------------------------------------DIRRDED-- 227
                  .|:| :|..:|.|.                                    |::.|..
Zfish   233 PIIFTHNPRP-ITCFYSPTQMPMQQPHGDSLTPDMRSANRLLVHPQNSPGRPFSSYDLKSDSGMR 296

  Fly   228 ---------------SDNQHKIN-----TDTIIIKPAVG-----------------AQDAGADDN 255
                           |..:|:.:     :.|:.:.|.:.                 .||:.:...
Zfish   297 PPAGFLHSGTSSPLVSGGRHQASVRSSCSYTLGLSPNISYRPPAPDPFMRHSGLYPRQDSPSQPR 361

  Fly   256 PDET-------------ILRRSKEKRAQK-------TDAEIYVELRAICNSDDPRERYKTTQEVG 300
            |..|             ..|..::...:.       |..:....|:.:.:..|||...:...::|
Zfish   362 PSPTGSLAHSPPGTCSPAFRAPQQPSPRPPPDPPKVTHEQFKAALQMVVDKGDPRSYLENFVKIG 426

  Fly   301 KGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQL 365
            :|::|:|.||.:..:...||||.:|::.|..::|:..|:.:::|:.|:|:|....:.|:  |::|
Zfish   427 EGSTGVVCIAREKHSGRVVAVKMMDLRRQQRRELLFNEVVIMRDYQHRNVVEMFKSALV--EEEL 489

  Fly   366 WVVMEYMDGGPLTDVVTETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKV 430
            ||:|||:.||.||::|:||.:.|.|||.||...|.|:::||::|:||||||||::||.:||.:|:
Zfish   490 WVIMEYLQGGALTNIVSETRLSEEQIATVCEAVLQALAYLHSQGVIHRDIKSDSILLSLDGRIKL 554

  Fly   431 TDFGFCANIEGD-EKRQTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPL 494
            :||||||.|..| .||:::|||||||||||:::..||.:||:||:|||.:||::|:|||..|||:
Zfish   555 SDFGFCAQISKDIPKRKSLVGTPYWMAPEVISKSPYGTEVDVWSLGIMVVEMVDGEPPYFSETPV 619

  Fly   495 RALYLIAANGRPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIK 559
            .|:..:.....|.:::..::||.|:|||||.|..:...||:|.:||.||||...|..:.|||.::
Zfish   620 AAMKRLRDELAPTVRNVHQVSPMLKDFLDRMLTRDPLERASATDLLEHPFLLQASSPQCLVPLVE 684

  Fly   560 AAKKVLRR 567
            ..:|.:.|
Zfish   685 QYRKRMSR 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	16/53 (30%)
		PKc_like	288..545	CDD:304357	117/257 (46%)
		S_TKc	293..545	CDD:214567	114/252 (45%)
LOC100536197	XP_003200338.1	CRIB_PAK_like	10..55	CDD:238526	16/51 (31%)
		PKc_like	397..693	CDD:304357	127/298 (43%)
		S_TKc	424..670	CDD:214567	114/247 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.780