Protein Alignment Pak3 and pak6

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_017952376.1
• Gene: pak6 / 100495355
• XenbaseID: XB-GENE-960331
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 703
• Identity: 207/703 - (29%)
• Similarity: 322/703 - (45%)
• Gaps: 196/703 - (27%)

  Fly     3 FTKWFKKKGGDGGSISEIGAPTNFQRHFHVSRNQETGDLEGLPAPWVRLMN-----------SQI 56
            |.|..||:       .||.||.|||...|.|.:.:.|...|||..|..:::           |:|
 Frog     2 FRKKKKKR-------PEISAPLNFQHRVHTSFDAKEGKFVGLPPQWQNVLDTLRRPKPVVDPSRI 59

  Fly    57 TR-------------------------DEQDK-----------NPDAAYHAVKYYNYSIKKKENE 85
            |:                         .:.:|           :|.|...|   .:..:..:|..
 Frog    60 TQVQLKPMKTVVRGSTIGLEGYISGLLHDIEKLSVISSNTLRGSPLARRRA---QSLGVLGEEKP 121

  Fly    86 VFKPF-ITEDVIHEESKEIENYVNYKN-----------------------------KHKSQDP-- 118
            :..|| |.|.:   .|.:..||:|...                             |.||.||
 Frog   122 LNGPFQIPEQI---PSDKYGNYINCNGESKASRRQTMWPDYRPVEDNYCKPNGSVFKAKSLDPGD 183

  Fly   119 ------------------------EKSDDDGSSTATETE-----SSSGCGSSAGNSNSSSINDSS 154
                                    .||.|:.:.|:.:..     |....|::|.|::|::.:...
 Frog   184 FQGTVDLMALSIPSPSSLQKAHIASKSFDEETPTSRQLSQIVPVSPREEGTAAKNTDSTTKHKLL 248

  Fly   155 QQSTVPLDALEEVFKELKTNLEHRETLKAAPQEPP------------PVPPKKSPHTIP------ 201
            :.:.||....:.|  ||   |...:.:|:...:.|            .:||.   |..|
 Frog   249 RGAFVPSSRGQSV--EL---LAPAQQIKSEALQGPSSSARGVFAKAASLPPN---HLSPDFTRVI 305

  Fly   202 ---------------PKPQIKPKPRVTQKFSRTSDIRRDEDSDNQHKINTDTIIIKPAVGAQDAG 251
                           |.|...|:.|..|    ||       |.|.| :.|||.      |....|
 Frog   306 SGAPSDSISPLRPCRPSPAGSPRSRPIQ----TS-------STNLH-LCTDTF------GKTQLG 352

  Fly   252 ADDNPDETILRRSKEKRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIVFIAADLQNE 316
            ..::|   ::...:.|.|          ||.:.:..|||:..:...::|:|::|:|.||.:..:.
 Frog   353 NQESP---VVTHEQFKTA----------LRMVVDQGDPRQLLEDYVKIGEGSTGVVCIAREKHSG 404

  Fly   317 SQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVNFLDAYLLEPEDQLWVVMEYMDGGPLTDVV 381
            .|||||.:|::.|..::|:..|:.:::|:.|.::|....:||:  .::|||:|||:.||.|||:|
 Frog   405 RQVAVKMMDLRKQQRRELLFNEVVIMRDYQHPSVVEMYKSYLV--GEELWVLMEYVQGGALTDIV 467

  Fly   382 TETVMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSVKVTDFGFCANIEGD-EKR 445
            ::|.:.|.|||.||:..|.|:.:||::|:||||||||::||.:||.:|::||||||.|..| .||
 Frog   468 SQTRLNEEQIATVCKSVLQALEYLHSQGVIHRDIKSDSILLTLDGRIKLSDFGFCAQISKDVPKR 532

  Fly   446 QTMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRALYLIAANGRPDIKS 510
            :::|||||||||||:.|..||.:|||||:|||.|||::|:|||..::|::|:..:..:..|.:|:
 Frog   533 KSLVGTPYWMAPEVILRCSYGTEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKN 597

  Fly   511 WDKLSPNLQDFLDRCLQVEVDRRATADELLSHPFLNDCSEVKALVPNIKAAKK 563
            ..|.||.|:|||:|.|..:...||||.|||.|.||......:.|||.|:..:|
 Frog   598 SHKASPILRDFLERMLVRDAAERATAQELLDHFFLLQAGLPECLVPLIQQYRK 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	21/100 (21%)
		PKc_like	288..545	CDD:304357	120/257 (47%)
		S_TKc	293..545	CDD:214567	117/252 (46%)
pak6	XP_017952376.1	CRIB_PAK_like	10..55	CDD:238526	14/44 (32%)
		STKc_PAK6	359..655	CDD:270821	131/304 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010