DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pak3 and map4k3

DIOPT Version :9

Sequence 1:	NP_001262638.1	Gene:	Pak3 / 41995	FlyBaseID:	FBgn0044826	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_012818238.1	Gene:	map4k3 / 100170570	XenbaseID:	XB-GENE-951441	Length:	924	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	106/265 - (40%)
Similarity:	155/265 - (58%)	Gaps:	9/265 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 DPRERYKTTQEVGKGASGIVFIAADLQNESQVAVKTIDMKNQSSKDLILTEIRVLKDFNHKNLVN 352
            :|:|.::..|.:|.|..|.|:.|.::......|:|.|.::......::..||.::||..|.|:|.
Frog    11 NPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHTNIVA 75

  Fly   353 FLDAYLLEPEDQLWVVMEYMDGGPLTDVVTET-VMKERQIACVCRETLYAISFLHAKGIIHRDIK 416
            :..:||  ..|:||:.||:..||.|.|:...| .:.|:|||.|.||||..:.:||:||.:|||||
Frog    76 YFGSYL--RRDKLWICMEFCGGGSLQDIYHVTGPLSEQQIAYVSRETLQGLYYLHSKGKMHRDIK 138

  Fly   417 SDNVLLGMDGSVKVTDFGFCANIEGD-EKRQTMVGTPYWMAPEV--VTRK-KYGKKVDIWSIGIM 477
            ..|:||..:|.||:.|||..|.|... .||::.:||||||||||  |.|| .|.:..|||::||.
Frog   139 GANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGIT 203

  Fly   478 AIEMIEGQPPYLYETPLRALYLIAANG--RPDIKSWDKLSPNLQDFLDRCLQVEVDRRATADELL 540
            :||:.|.|||.....|:|||:|:..:.  .|.:|...|.|.:...|:...|.....:|.||::||
Frog   204 SIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFIKMALTKNPKKRPTAEKLL 268

  Fly   541 SHPFL 545
            .||||
Frog   269 QHPFL 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166
		PKc_like	288..545	CDD:304357	104/263 (40%)
		S_TKc	293..545	CDD:214567	102/258 (40%)
map4k3	XP_012818238.1	STKc_MAP4K3_like	15..272	CDD:270788	101/258 (39%)
		S_TKc	16..273	CDD:214567	102/258 (40%)
		CNH	591..904	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910