Protein Alignment Pak3 and lats1

DIOPT Version :9

• Sequence 1: NP_001262638.1
• Gene: Pak3 / 41995
• FlyBaseID: FBgn0044826
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_017949762.1
• Gene: lats1 / 100145677
• XenbaseID: XB-GENE-959763
• Length: 1117
• Species: Xenopus tropicalis
• Alignment Length: 690
• Identity: 149/690 - (21%)
• Similarity: 249/690 - (36%)
• Gaps: 213/690 - (30%)

  Fly     4 TKWFKKKGGDGGSISEIGAPTNFQRHFHVS-----RNQETGDLE-------GLPAPWVRLMNSQI 56
            |...:.:.|.||.:|     :|...:.:|.     .|:.:.:||       |.|..|.:..::|.
 Frog   375 TTTLQVQSGSGGPLS-----SNAYNNSNVPPSMLVSNRNSHNLEMYNISLPGHPTSWPQASSTQS 434

  Fly    57 ----------------TRDEQDKNPDAAYHAVKYYNYS------------IKK--KENEVFKPFI 91
                            .|.....||.|::.|:.....:            |::  |...|.||.:
 Frog   435 APGSNHDMLSWQTNIPVRSNSFNNPVASWQALSTNTQTSATTVTAVTPSPIQQPVKSIRVLKPEL 499

  Fly    92 ---------------------TEDVIHEESKEIENYVNYKN------KHKSQ------DP----E 119
                                 .|.|.|..|.::....||:.      ||..|      :|    .
 Frog   500 QTALAPTHPTWMTPNVQPGPFQEGVSHNTSAQLAEAPNYQGPPPPYPKHLLQQNTTVYEPGLKSS 564

  Fly   120 KSDDDGSSTATETESSSGCGSSAGNSNSSSINDSSQQSTVPLDALEEVFKELKTNLEHRETLKAA 184
            |.|..|.||.|:.|.......:.|      |.:..|.:|.|:..     :..|.:.|.||:
 Frog   565 KEDAAGVSTCTQEEMEKNTEPTTG------ITEKKQITTSPVPV-----RRNKRDEERRES---- 614

  Fly   185 PQEPPPVPPKKSPHTIPPKPQIKPKPRVTQKFSRTSDIRRDEDSDNQ---HKINTDTIIIKPAVG 246
                                ||:.......||.....:.....|.:|   .|...:..:::..:.
 Frog   615 --------------------QIQSYSPQAFKFFMEQHVENILKSHHQRLHRKKQLENEMMRVGLS 659

  Fly   247 AQDAGADDNPDETILRRSKE----KRAQKTDAEIYVELRAICNSDDPRERYKTTQEVGKGASGIV 307
            .:   |.|...:.:.::...    ||| |.:..::|:::.:                |.||.|.|
 Frog   660 QE---AQDQMRKMLCQKESNYIRLKRA-KMEKSMFVKIKTL----------------GIGAFGEV 704

  Fly   308 FIAADLQNESQVAVKTIDMKNQSSKDLIL--------TEIRVLKDFNHKNLVNFLDAYLLEPEDQ 364
            .:|......:..|:||:     ..||::|        .|..:|.:.:::.:|...  |..:.:|.
 Frog   705 CLARKTDTNALYAMKTL-----RKKDVLLRNQVAHVKAERDILAEADNEWVVRLY--YSFQDKDN 762

  Fly   365 LWVVMEYMDGGPLTDVVTET-VMKERQIACVCRETLYAISFLHAKGIIHRDIKSDNVLLGMDGSV 428
            |:.||:|:.||.:..::... |..|........|...|:..:|....||||||.||:|:..||.:
 Frog   763 LYFVMDYIPGGDMMSLLIRMGVFPEDLARFYIAELTCAVESVHKMDFIHRDIKPDNILIDRDGHI 827

  Fly   429 KVTDFGFCANI----------EGDEKRQ------------------------------------- 446
            |:||||.|...          .||..||
 Frog   828 KLTDFGLCTGFRWTHDSKYYQSGDHLRQDSMDFSNEWGDPANCRCGDRLKPLEWRAARQHQRCLA 892

  Fly   447 -TMVGTPYWMAPEVVTRKKYGKKVDIWSIGIMAIEMIEGQPPYLYETPLRA-LYLIAANGRPDIK 509
             ::||||.::||||:.|..|.:..|.||:|::..||:.||||:|.::|:.. :.:|.......|.
 Frog   893 HSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILYEMLVGQPPFLAQSPVETQMKVIKWQTTLHIP 957

  Fly   510 SWDKLSPNLQDFLDRCLQVEVDR--RATADELLSHPFLND 547
            :..||||...|.:.:..:...||  :...||:..|||..:
 Frog   958 AQAKLSPEASDLIVKLCRGPEDRLGKNGVDEIKVHPFFKN 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pak3	NP_001262638.1	PBD	19..73	CDD:279166	14/81 (17%)
		PKc_like	288..545	CDD:304357	84/316 (27%)
		S_TKc	293..545	CDD:214567	84/311 (27%)
lats1	XP_017949762.1	UBA_LATS1	102..142	CDD:270580
		STKc_LATS1	688..1069	CDD:270775	86/333 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910