Protein Alignment Ttc1 and TOM70

DIOPT Version :10

• Sequence 1: NP_650543.1
• Gene: Ttc1 / 41993
• FlyBaseID: FBgn0038428
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_014278.3
• Gene: TOM70 / 855602
• SGDID: S000005065
• Length: 617
• Species: Saccharomyces cerevisiae
• Alignment Length: 243
• Identity: 69/243 - (28%)
• Similarity: 108/243 - (44%)
• Gaps: 49/243 - (20%)

  Fly    19 ITEKEATSTRQSEKDVDEIVEKQNQLALDDEAEQGAAGGDSIATPTTVDSELTIEELREREKDLS 83
            |.:.|...|:.|:|:.             :.|::..|..:....|.:.:.          |.|.|
Yeast    44 INKDEKKDTKDSQKET-------------EGAKKSTAPSNPPIYPVSSNG----------EPDFS 85

  Fly    84 PE-QLTANKEKADK----LKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAK 143
            .: ..||  |:.||    ||.:||:.|:|...:.|.|.|..||::      ||..|.|.|.:|..
Yeast    86 NKANFTA--EEKDKYALALKDKGNQFFRNKKYDDAIKYYNWALEL------KEDPVFYSNLSACY 142

  Fly   144 IKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEIDPGQQEAREAQI 208
            :.:...|..::..|||:||.|:|.:||||||...|...|..:|:.|. .|..::....:|
Yeast   143 VSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDL-SVLSLNGDFNDA----- 201

  Fly   209 RLPPIINERNEKLKNEMMSSLK----DLGNMILKPFGLSTQNFQMQQD 252
            .:.|:: |||  |..:.||.||    |:......|..||||..:.::|
Yeast   202 SIEPML-ERN--LNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKD 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ttc1	NP_650543.1	3a0801s09	16..>232	CDD:273380	62/221 (28%)
		TPR repeat	94..122	CDD:276809	12/31 (39%)
		TPR repeat	132..162	CDD:276809	8/29 (28%)
		TPR repeat	167..195	CDD:276809	11/27 (41%)
TOM70	NP_014278.3	3a0801s09	1..614	CDD:273380	69/243 (28%)
		TPR repeat	99..127	CDD:276809	10/27 (37%)
		TPR repeat	131..161	CDD:276809	8/29 (28%)
		TPR repeat	166..189	CDD:276809	9/22 (41%)
		TPR repeat	330..358	CDD:276809
		TPR repeat	363..391	CDD:276809
		TPR repeat	396..426	CDD:276809
		TPR repeat	431..459	CDD:276809
		TPR repeat	465..493	CDD:276809
		TPR repeat	498..537	CDD:276809
		TPR repeat	542..567	CDD:276809