Protein Alignment Ttc1 and SGT2

DIOPT Version :10

• Sequence 1: NP_650543.1
• Gene: Ttc1 / 41993
• FlyBaseID: FBgn0038428
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_014649.1
• Gene: SGT2 / 854168
• SGDID: S000005533
• Length: 346
• Species: Saccharomyces cerevisiae
• Alignment Length: 283
• Identity: 74/283 - (26%)
• Similarity: 114/283 - (40%)
• Gaps: 56/283 - (19%)

  Fly    17 EEITEKEATSTRQSEKDVDEIVEKQNQLALDDEAEQGAAG-----GDSIATPTTVDSELTIEELR 76
            :||:|..|.|...:...:.|      ....:.||..|..|     |..:|......|.:.....:
Yeast    23 KEISEDGADSLNVAMDCISE------AFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKK 81

  Fly    77 EREKDLS---PEQLTANKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGN 138
            :..:::.   ||.....|.||:.||::||:...|.|.|.|...||||:.:.|:     .|:.|.|
Yeast    82 DDAENVEINIPEDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPT-----NAIYYAN 141

  Fly   139 RAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEID------ 197
            ||||...|:....|:.|...||.:.|.|.|...|.......:.||:||||.||||.:|:
Yeast   142 RAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATE 206

  Fly   198 ------PGQQEAREAQIRLPPIINERN-----EKLKNEMMSSLKDLGNMILKPFG---------- 241
                  ...::..|..:.|...:.|::     :..:......|.|||:::....|
Yeast   207 AMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASAGGLPDLGSLLGGGLGGLMNNPQLMQ 271

  Fly   242 -----LST----QNFQ-MQQDPN 254
                 :|.    ||.| |.|||:
Yeast   272 AAQKMMSNPGAMQNIQKMMQDPS 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ttc1	NP_650543.1	3a0801s09	16..>232	CDD:273380	62/239 (26%)
		TPR repeat	94..122	CDD:276809	13/27 (48%)
		TPR repeat	132..162	CDD:276809	12/29 (41%)
		TPR repeat	167..195	CDD:276809	12/27 (44%)
SGT2	NP_014649.1	SGTA_dimer	7..71	CDD:465168	12/53 (23%)
		NlpI	41..221	CDD:443815	53/190 (28%)
		TPR repeat	102..130	CDD:276809	13/27 (48%)
		TPR repeat	135..165	CDD:276809	12/29 (41%)
		TPR repeat	170..198	CDD:276809	12/27 (44%)
		STI1	264..298	CDD:128966	8/31 (26%)