DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and TPR1

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_194777.3	Gene:	TPR1 / 829171	AraportID:	AT4G30480	Length:	277	Species:	Arabidopsis thaliana

Alignment Length:	275	Identity:	93/275 - (33%)
Similarity:	152/275 - (55%)	Gaps:	19/275 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NANSDDEF---HDAIGEEITEKEATSTRQSEKDVDEIVEKQNQLAL-DDEAEQGAAGGDSIATPT 64
            ::.|:||.   ::......:..:.|.|:|.:.|..:..|..::..: |:|.|:.....|::
plant     6 SSESEDEILIKNEPKPASSSSPQPTETKQVDGDDSDGFETASEREISDEEGEEDGTKNDAV---- 66

  Fly    65 TVDSELTIEELREREKDLSPEQLT-----ANKEK----ADKLKVEGNELFKNDDAEGAAKTYTEA 120
            |...|....|.:|.:.:|..|...     :||||    |::.|.|||:||.|...|.|...|..|
plant    67 TSQEEPQHSEKKEEQIELMSEGEAIVDDGSNKEKALAEANEAKAEGNKLFVNGLYEEALSKYAFA 131

  Fly   121 LDICPS--ASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKP 183
            |::...  .|.:.|::.|.||....:||...:..|.:||||:||.|.|.:.|:|||:.:|:.:..
plant   132 LELVQELPESIELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHF 196

  Fly   184 DEALEDYKKVTEIDPGQQEAREAQIRLPPIINERNEKLKNEMMSSLKDLGNMILKPFGLSTQNFQ 248
            ::|:.|.||:.|:||...:||:...||.|:..|:.||:|.|.::.||::||.||..||:|..||:
plant   197 EDAVTDLKKILELDPSNDQARKGIRRLEPLAAEKREKMKEEAITKLKEMGNSILGRFGMSVDNFK 261

  Fly   249 MQQDPNTGSYSINFK 263
            ..:||||||||::|:
plant   262 AVKDPNTGSYSLSFQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	28/76 (37%)
		TPR repeat	94..122	CDD:276809	12/27 (44%)
		TPR_11	132..198	CDD:290150	25/65 (38%)
		TPR repeat	132..162	CDD:276809	11/29 (38%)
		TPR_1	133..166	CDD:278916	13/32 (41%)
		TPR	167..198	CDD:197478	10/30 (33%)
		TPR repeat	167..195	CDD:276809	9/27 (33%)
TPR1	NP_194777.3	TPR_11	104..177	CDD:290150	27/72 (38%)
		TPR repeat	105..133	CDD:276809	12/27 (44%)
		TPR repeat	138..175	CDD:276809	12/36 (33%)
		TPR_11	145..211	CDD:290150	25/65 (38%)
		TPR	148..179	CDD:197478	13/30 (43%)
		TPR repeat	180..208	CDD:276809	9/27 (33%)
		TPR_1	181..213	CDD:278916	12/31 (39%)
		TPR repeat	214..244	CDD:276809	11/29 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I3549
eggNOG	1	0.900	-	-		E1_KOG4234
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2485
Inparanoid	1	1.050	144	1.000	Inparanoid score	I1759
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1418232at2759
OrthoFinder	1	1.000	-	-		FOG0006488
OrthoInspector	1	1.000	-	-		oto3759
orthoMCL	1	0.900	-	-		OOG6_103243
Panther	1	1.100	-	-	LDO	PTHR46014
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.920