DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and tomm70a

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_956296.1	Gene:	tomm70a / 572969	ZFINID:	ZDB-GENE-030131-8173	Length:	578	Species:	Danio rerio

Alignment Length:	188	Identity:	63/188 - (33%)
Similarity:	89/188 - (47%)	Gaps:	19/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EKQNQLALDDEAEQGAAGGDSIATPTTVDSELTIEELREREKDLSPEQLTANKEKADKLKVEGNE 103
            |||.:...:.:..:|:      |:|.......|..||    ::|||      .::|...|.:||:
Zfish    45 EKQGKRNGERKTPEGS------ASPVQGQHGATNPEL----ENLSP------LDRAQSAKNKGNK 93

  Fly   104 LFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVR 168
            .||....:.|.|.||||:.:||.....:.:..|.|||||..:.......|.||::|:||.|.||:
Zfish    94 YFKAGKYDHAIKCYTEAIGLCPKEKKGDLSTFYQNRAAAYEQQMKWTEVIQDCSQAVELNPRYVK 158

  Fly   169 VLLRRAKLYEQEDKPDEALEDYKKV--TEIDPGQQEAREAQIRLPPIINER-NEKLKN 223
            .|.||||..|:.|...|.|||...|  .|:...||....|...|..:..|: .||.||
Zfish   159 ALFRRAKALEKLDNKKECLEDVTAVCILEVFQNQQSMLLADKVLKQLGKEKAKEKYKN 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	26/70 (37%)
		TPR repeat	94..122	CDD:276809	12/27 (44%)
		TPR_11	132..198	CDD:290150	28/67 (42%)
		TPR repeat	132..162	CDD:276809	10/29 (34%)
		TPR_1	133..166	CDD:278916	13/32 (41%)
		TPR	167..198	CDD:197478	14/32 (44%)
		TPR repeat	167..195	CDD:276809	13/29 (45%)
tomm70a	NP_956296.1	TPR_11	83..154	CDD:290150	26/70 (37%)
		TPR_1	84..116	CDD:278916	13/31 (42%)
		TPR repeat	84..112	CDD:276809	12/27 (44%)
		TPR repeat	122..152	CDD:276809	10/29 (34%)
		TPR	277..560	CDD:223533
		TPR repeat	299..327	CDD:276809
		TPR repeat	336..366	CDD:276809
		TPR repeat	371..399	CDD:276809
		TPR repeat	446..474	CDD:276809
		TPR repeat	479..510	CDD:276809
		TPR repeat	515..542	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594913at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920