DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and unc-45

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001303425.1	Gene:	unc-45 / 44910	FlyBaseID:	FBgn0010812	Length:	947	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	57/161 - (35%)
Similarity:	84/161 - (52%)	Gaps:	13/161 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 TANKEK---ADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEAN 149
            |.|.|:   |...|.:|||.||....|.|.:.|.:|  |...:..||.||.|.|||||.:||...
  Fly     4 TINSEEVSDAGSYKDKGNEAFKASRWEEAVEHYGKA--IKAGSKHKELAVFYKNRAAAYLKLGKY 66

  Fly   150 KAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEIDPGQQEAREAQIRLPPII 214
            :.|::|||::::..|...:.|.|||:.||..:|.:||.:|...:.:.|||.:..:....||..::
  Fly    67 ENAVEDCTESLKAAPGDPKALFRRAQAYEALEKFEEAYKDATALFKADPGNKTVQPMLQRLHVVV 131

  Fly   215 NER-------NEKLKNEMMSSLKDLGNMILK 238
            .||       :.|:| :||....||...|.|
  Fly   132 EERSARNAKTSTKVK-QMMDLTFDLATPIDK 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	28/73 (38%)
		TPR repeat	94..122	CDD:276809	11/27 (41%)
		TPR_11	132..198	CDD:290150	25/65 (38%)
		TPR repeat	132..162	CDD:276809	14/29 (48%)
		TPR_1	133..166	CDD:278916	15/32 (47%)
		TPR	167..198	CDD:197478	10/30 (33%)
		TPR repeat	167..195	CDD:276809	10/27 (37%)
unc-45	NP_001303425.1	TPR_11	12..81	CDD:290150	28/70 (40%)
		TPR repeat	16..41	CDD:276809	10/26 (38%)
		TPR repeat	46..79	CDD:276809	16/32 (50%)
		TPR_11	50..115	CDD:290150	25/64 (39%)
		TPR	50..83	CDD:197478	15/32 (47%)
		UNC45-central	351..494	CDD:288539
		ARM	668..788	CDD:237987
		armadillo repeat	753..789	CDD:293788
		armadillo repeat	795..826	CDD:293788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840