DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and Stip1

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_477354.1	Gene:	Stip1 / 33202	FlyBaseID:	FBgn0024352	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	66/190 - (34%)
Similarity:	91/190 - (47%)	Gaps:	25/190 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LREREKDLSPEQLTA--NKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYG 137
            |.|.|..:..|:..|  |.|||::.|.:||..||..|...|.|.||||:...|     :...||.
  Fly   289 LSEVEAKIKEEERMAYINPEKAEEEKEQGNLFFKKGDYSTAVKHYTEAIKRNP-----DDPKLYS 348

  Fly   138 NRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEIDPGQQE 202
            ||||...||.|....:.||...|:|..::::..:|:.|:.:...:..:|...|:|..|:||...|
  Fly   349 NRAACYTKLAAFDLGLKDCDTCIKLDEKFIKGYIRKGKILQGMQQQSKAQAAYQKALELDPNNAE 413

  Fly   203 AREAQIRLPPIINERN--EKLKN-----EMMSSLKDLG-NMILKPFGLSTQNFQMQQDPN 254
            |.|. .|...:..:||  |.|||     |:...|||.. .|||:         |||.|||
  Fly   414 AIEG-YRQCSMNFQRNPQEVLKNAMSDPEIQQILKDPAMRMILE---------QMQSDPN 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	28/70 (40%)
		TPR repeat	94..122	CDD:276809	13/27 (48%)
		TPR_11	132..198	CDD:290150	19/65 (29%)
		TPR repeat	132..162	CDD:276809	12/29 (41%)
		TPR_1	133..166	CDD:278916	13/32 (41%)
		TPR	167..198	CDD:197478	6/30 (20%)
		TPR repeat	167..195	CDD:276809	5/27 (19%)
Stip1	NP_477354.1	TPR_11	6..69	CDD:290150
		TPR repeat	7..32	CDD:276809
		TPR repeat	37..67	CDD:276809
		TPR_11	40..103	CDD:290150
		TPR repeat	72..100	CDD:276809
		TPR_11	175..237	CDD:290150
		TPR repeat	175..203	CDD:276809
		TPR_1	181..208	CDD:278916
		TPR_12	205..278	CDD:290160
		TPR repeat	208..238	CDD:276809
		TPR repeat	250..278	CDD:276809
		TPR_1	250..>276	CDD:278916
		TPR_11	309..375	CDD:290150	28/70 (40%)
		TPR repeat	310..338	CDD:276809	13/27 (48%)
		TPR_1	<317..343	CDD:278916	12/30 (40%)
		TPR repeat	343..373	CDD:276809	12/29 (41%)
		TPR_1	378..411	CDD:278916	8/32 (25%)
		TPR repeat	378..406	CDD:276809	5/27 (19%)
		STI1	439..478	CDD:128966	13/34 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840