DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and Tomm70

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_997684.1	Gene:	Tomm70 / 304017	RGDID:	1303049	Length:	610	Species:	Rattus norvegicus

Alignment Length:	180	Identity:	62/180 - (34%)
Similarity:	95/180 - (52%)	Gaps:	13/180 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 AGGDSIATPTTVDSELTIEELRERE-----KDLSPEQL-TANKEKADKLKVEGNELFKNDDAEGA 113
            |||...|:....:||....|.|...     .|.|.:.| .::.::|...|.:||:.||....|.|
  Rat    71 AGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQA 135

  Fly   114 AKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYE 178
            .:.||||:.:||:..:.:.:..|.|||||..:|:..|....|||||:||.|:||:.|.||||.:|
  Rat   136 IQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHE 200

  Fly   179 QEDKPDEALEDYKKVTEIDPGQQEAREAQI---RLPPIINERN--EKLKN 223
            :.|...|.|||...|..::..|.|  ::.:   ::..::.:.|  ||.||
  Rat   201 KLDNKKECLEDVTAVCILEGFQNE--QSMLLADKVLKLLGKENAKEKYKN 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	29/70 (41%)
		TPR repeat	94..122	CDD:276809	12/27 (44%)
		TPR_11	132..198	CDD:290150	30/65 (46%)
		TPR repeat	132..162	CDD:276809	13/29 (45%)
		TPR_1	133..166	CDD:278916	16/32 (50%)
		TPR	167..198	CDD:197478	13/30 (43%)
		TPR repeat	167..195	CDD:276809	13/27 (48%)
Tomm70	NP_997684.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	69..109		10/37 (27%)
		3a0801s09	<116..603	CDD:273380	51/135 (38%)
		TPR 1	116..149		14/32 (44%)
		TPR repeat	116..144	CDD:276809	12/27 (44%)
		TPR repeat	149..184	CDD:276809	13/34 (38%)
		TPR 2	155..188		16/32 (50%)
		TPR 3	296..329
		TPR 4	331..364
		TPR repeat	331..359	CDD:276809
		TPR repeat	364..398	CDD:276809
		TPR 5	369..402
		TPR 6	403..436
		TPR repeat	403..431	CDD:276809
		TPR 7	444..477
		TPR repeat	446..472	CDD:276809
		TPR 8	478..511
		TPR repeat	478..506	CDD:276809
		TPR repeat	511..542	CDD:276809
		TPR 9	513..546
		TPR 10	547..580
		TPR repeat	547..574	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D594913at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920