DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14894 and ttc-1

DIOPT Version :9

Sequence 1:	NP_001262636.1	Gene:	CG14894 / 41993	FlyBaseID:	FBgn0038428	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_492795.1	Gene:	ttc-1 / 172965	WormBaseID:	WBGene00016390	Length:	207	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	74/194 - (38%)
Similarity:	112/194 - (57%)	Gaps:	11/194 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 IEELREREKDLSPEQLTANKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLY 136
            |||:.|.|:|    |:|    |.|.||.|||..|.|.:.|.|.:.|.||:..||..|::.:::|.
Worm     4 IEEIFEDEED----QIT----KVDSLKKEGNNFFANGEFEKANEKYQEAIASCPPTSTEVQSILL 60

  Fly   137 GNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLY-EQEDKPDEALEDYKKVTEIDPGQ 200
            .|.|||.|||...::|::..:|:||:.....:.|.|||..| ...:|.:.::||||::.|..|.:
Worm    61 SNSAAALIKLRKWESAVEAASKSIEIGATNEKALERRAFAYSNMSEKYENSIEDYKQLQESLPKR 125

  Fly   201 QEAREAQI-RLPPIINERNEKLKNEMMSSLKDLGNMILKPFGLSTQNFQMQQDPNTGSYSINFK 263
            :...:.:| .:...||.|||.:|.::|..||..||..|.||||||.:|:|..:.| |.:|:..|
Worm   126 RVELDRKIAEINEKINNRNEAMKADVMEKLKGFGNFCLSPFGLSTDSFEMVPNGN-GGFSVQMK 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14894	NP_001262636.1	TPR_11	93..164	CDD:290150	29/70 (41%)
		TPR repeat	94..122	CDD:276809	13/27 (48%)
		TPR_11	132..198	CDD:290150	23/66 (35%)
		TPR repeat	132..162	CDD:276809	11/29 (38%)
		TPR_1	133..166	CDD:278916	12/32 (38%)
		TPR	167..198	CDD:197478	11/31 (35%)
		TPR repeat	167..195	CDD:276809	10/28 (36%)
ttc-1	NP_492795.1	TPR repeat	18..46	CDD:276809	13/27 (48%)
		3a0801s09	<20..>115	CDD:273380	34/94 (36%)
		TPR repeat	56..86	CDD:276809	11/29 (38%)
		TPR repeat	91..120	CDD:276809	10/28 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4234
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I3376
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53302
OrthoDB	1	1.010	-	-		D1418232at2759
OrthoFinder	1	1.000	-	-		FOG0006488
OrthoInspector	1	1.000	-	-		oto18638
orthoMCL	1	0.900	-	-		OOG6_103243
Panther	1	1.100	-	-	LDO	PTHR46014
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3538
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910