Protein Alignment ema and clec16a

DIOPT Version :9

• Sequence 1: NP_650542.1
• Gene: ema / 41992
• FlyBaseID: FBgn0038427
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: XP_003198156.1
• Gene: clec16a / 393184
• ZFINID: ZDB-GENE-040426-951
• Length: 1046
• Species: Danio rerio
• Alignment Length: 1077
• Identity: 497/1077 - (46%)
• Similarity: 653/1077 - (60%)
• Gaps: 156/1077 - (14%)

  Fly     1 MF-RSRSWFGGPWGGRPKNRLSLEHLKYLYSILEKNTTVSESNRGLLVESLRCIAEILIWGDQHD 64
            || |||||.||.  |:.||..||:||||:|.:|.|||||::.||.||||::|.|.||||||||:|
Zfish     1 MFGRSRSWVGGQ--GKSKNIHSLDHLKYMYHVLTKNTTVTDHNRNLLVETIRSITEILIWGDQND 63

  Fly    65 SLVFDFFLEKNMLSYFLHIMRQKSGGSSFVCVQLLQTLNILFENIRNETSLYYLLSNNHVNSIMV 129
            |.||||||||||.::||:|:|||||  .:||||||||||||||||.:||||||||||||||||:|
Zfish    64 SSVFDFFLEKNMFAFFLNILRQKSG--RYVCVQLLQTLNILFENISHETSLYYLLSNNHVNSIIV 126

  Fly   130 HKFDFSDEDVMGYYILFLKTLSLKLNTHTIHFFYNEHTNDFPLYTEAIKFFNHPESMVRIAVRTI 194
            ||||||||::|.|||.||||||||||.||:|||||||||||.|||||||||||||||||||||||
Zfish   127 HKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTI 191

  Fly   195 SLNVYKV--QNPSMLRFIRDKTAAPYFSNLVWFIGKHILELDTCVRTDIDHQSNQKLSNLVAEHL 257
            :||||||  .|..||.:||||||.|||||||||||.|::|||.||:||.:|::..|||:||||||
Zfish   192 TLNVYKVSLDNQHMLHYIRDKTAVPYFSNLVWFIGSHVIELDKCVQTDEEHKNRGKLSDLVAEHL 256

  Fly   258 DHLHYLSDILLLEIKDLNAVLTEHLLHKLFVPLYIFSLTPAPPPPSLAVVTQNLAAVLNRNVDID 322
            ||||||:|||.:..:.||.|||:|||::||:|||::||           |||
Zfish   257 DHLHYLNDILTINCEFLNDVLTDHLLNRLFLPLYVYSL-----------VTQ------------- 297

  Fly   323 IQEMHNPRVSSIVALFLLSLVFLVVSHAPLVHALAWVILNGDHSVF---KEGAAEILNSYVEHRE 384
             ::..:.:::..|:|:|||.|||::.:.||||:||.||||||.|||   .|.:|...:|....|.
Zfish   298 -EQTEDRKINPQVSLYLLSQVFLIIHYQPLVHSLADVILNGDLSVFTLQTEQSAHKSSSNAGVRR 361

  Fly   385 VVVPGFGEPDESLEQALDTV----------------TGQSSSSSYALSEDSGVESSSPATTELDS 433
                 |.:|.||||::|:..                .|:.........|....|......||..|
Zfish   362 -----FTKPLESLERSLEMSRQRGRKRAQKRPNYKNVGEEEEEKRGSDEGPEEEKEKAKGTEASS 421

  Fly   434 QA-----DAVEAEQIKL-------------RNITDEEKQLLQKSSSSTKADFAEMAKPFLDTVLH 480
            :|     |..|.|.:.:             :||||||     ||:::......:.::||||.:..
Zfish   422 KASRTSGDKEEIEMVVMEKCRISDVSTLTEQNITDEE-----KSAAAAARSEGQKSRPFLDMLYS 481

  Fly   481 ALDCTENDYLALLSLCLIYAMSHNRGIKNEWFEQV-LAKSTRGAFSYKTALIEHLLNIITQSSQP 544
            ||||...||.||..|||:|||||::||..|..|:: |...::...:|...|:|.::.|::|::||
Zfish   482 ALDCDTEDYQALFVLCLLYAMSHSKGINPELLERIQLPVPSQERNTYSQVLVERVIRIMSQAAQP 546

  Fly   545 SSRIRLITVEIALELLVTFTRPSSDDSRCITAAQQDL----LFSARNQSMVVIRNFYKSEDIFLD 605
            ..::||.|:|::..||   .:.....|:||.   :|:    |..||.:|:.::|.|||.|:||||
Zfish   547 DGKVRLATLELSCLLL---KQSVLSGSQCII---KDIHLACLEGAREESLHLLRQFYKGEEIFLD 605

  Fly   606 LFEDEYNEMRKAQLNVEFLCMDSTILLPPTGTPLTGINFTRRLPCGEVEKARRAIRVYFLLRRTC 670
            :|||||..|....||||:|.||::|||||||||||||:|.:|||||:||:.||||||:|:||...
Zfish   606 MFEDEYRSMMSKPLNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVERTRRAIRVFFMLRSLS 670

  Fly   671 QKFLNEKESLLPLTNVVNLVQVENVLDLNNSDLIACTVVAKDSSKQRRFLVIDALQLILVEPDAK 735
            .:...|.|:.||||...:|::.::||||||||||||.||:||..:.:|||.:|..|:.|||||:|
Zfish   671 LQLQGEPETQLPLTRPEDLIKTDDVLDLNNSDLIACMVVSKDGVQAQRFLAVDVYQMSLVEPDSK 735

  Fly   736 LLGWGVAKFVGFLQDVEVQGDKDDSRCLHITVHRGGVTHN----RTPLLSAKFLFDDHIRCMAAK 796
            .|||||.||.|.|||::|.|.:||||.|:|.:|:  .|.|    ..|:|.|.|:|.|||||:.||
Zfish   736 RLGWGVVKFAGLLQDMQVSGVEDDSRALNIIIHK--PTSNPHAKPMPILQANFIFADHIRCIIAK 798

  Fly   797 QRLTKGRSKARQKKMYQIAQLIEIPGQMDSPVYAVGGTMVASSSGGSGNSSGSSS------RSSH 855
            |||.|||.:||:.||.:||.|:::|.|..:.|.            |....|.:||      ..|.
Zfish   799 QRLAKGRIQARRMKMQRIAALLDLPVQPSTEVL------------GFSQPSVTSSLPFRFYDQSR 851

  Fly   856 HRPMFSTANRVPGFAAV-----LRGSNSAGVSRTQMAPNRSIEGIRNESAGRSRRR----SPSST 911
            ..|.|::.::|||||..     ...|:|:.||.:...|..|.:.:...:.....:.    :||.|
Zfish   852 RGPAFASVDKVPGFAVAHIAQHNSTSSSSSVSPSSSGPPDSCDSLTASNTSTQSQTGLALAPSLT 916

  Fly   912 SGS----NLRADHS-----------------DRERSPSVSMGSHSSSQSRENSQPRS--TGNRSR 953
            ...    :|.:|:.                 .|.||.|.........:....|:|..  ||.|..
Zfish   917 PAPQPTISLLSDNDAETLSVESLTLLPPADPPRLRSFSTQSSIQDEDEVANTSRPEDDCTGVRDA 981

  Fly   954 ESS-----PRMPRPRSEEIPL-----EDFQHSRNNSP 980
            :|.     |.......|..||     ||...::...|
Zfish   982 QSQDISIIPEEDESSPESGPLLAGETEDLMQAQREEP 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ema	NP_650542.1	FPL	50..199	CDD:313053	123/148 (83%)
clec16a	XP_003198156.1	FPL	49..196	CDD:286801	123/148 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574166
Domainoid	1	1.000	530	1.000	Domainoid score	I272
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H71019
Inparanoid	1	1.050	683	1.000	Inparanoid score	I678
OMA	1	1.010	-	-		QHG52345
OrthoDB	1	1.010	-	-		D1319544at2759
OrthoFinder	1	1.000	-	-		FOG0006421
OrthoInspector	1	1.000	-	-		oto40663
orthoMCL	1	0.900	-	-		OOG6_103636
Panther	1	1.100	-	-	LDO	PTHR21481
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4687
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910