Protein Alignment ema and clec16a

DIOPT Version :9

• Sequence 1: NP_650542.1
• Gene: ema / 41992
• FlyBaseID: FBgn0038427
• Length: 1067
• Species: Drosophila melanogaster
• Sequence 2: XP_004918003.1
• Gene: clec16a / 100488730
• XenbaseID: XB-GENE-1018324
• Length: 1110
• Species: Xenopus tropicalis
• Alignment Length: 1182
• Identity: 510/1182 - (43%)
• Similarity: 681/1182 - (57%)
• Gaps: 214/1182 - (18%)

  Fly     1 MF-RSRSWFGGPWGGRPKNRLSLEHLKYLYSILEKNTTVSESNRGLLVESLRCIAEILIWGDQHD 64
            || ||:||..| ..||..:..||:.|||:|.||.|||||::.||.||||::|.|.|||:||||:|
 Frog     1 MFGRSKSWVSG-GSGRSSSVHSLDRLKYMYHILTKNTTVTDLNRNLLVETIRSITEILLWGDQND 64

  Fly    65 SLVFDFFLEKNMLSYFLHIMRQKSGGSSFVCVQLLQTLNILFENIRNETSLYYLLSNNHVNSIMV 129
            |.||||||||||..:||:|:|||||  .:||.||||:||:|||||.:||||||||||||||||:|
 Frog    65 SSVFDFFLEKNMFVFFLNILRQKSG--RYVCGQLLQSLNMLFENINHETSLYYLLSNNHVNSIIV 127

  Fly   130 HKFDFSDEDVMGYYILFLKTLSLKLNTHTIHFFYNEHTNDFPLYTEAIKFFNHPESMVRIAVRTI 194
            ||||||||::|||||.||||||:|||.||:|||||||||||.|||||||||||||.|||||||.|
 Frog   128 HKFDFSDEEIMGYYICFLKTLSVKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPEHMVRIAVRNI 192

  Fly   195 SLNVYKV--QNPSMLRFIRDKTAAPYFSNLVWFIGKHILELDTCVRTDIDHQSNQKLSNLVAEHL 257
            :||:|||  .|..||.:||||||.|||||||||||.|::|||.||:||.:|::...|||||::||
 Frog   193 TLNIYKVSFNNQPMLHYIRDKTAVPYFSNLVWFIGIHVIELDKCVQTDEEHKNRGNLSNLVSQHL 257

  Fly   258 DHLHYLSDILLLEIKDLNAVLTEHLLHKLFVPLYIFSLTPAPPPPSLAVVTQNLAAVLNRNVDID 322
            |||:||:|||::..:.||.|||:|||::|.:|||::||           |||:
 Frog   258 DHLNYLNDILIINCEFLNDVLTDHLLNRLLLPLYVYSL-----------VTQD------------ 299

  Fly   323 IQEMHNPRVSSIVALFLLSLVFLVVSHAPLVHALAWVILNGDHSVFKEGAAEILNSYVEH----- 382
             :....||:|..|||:|||.|||.:.:||||:.||.||||||.|||        :|..||
 Frog   300 -EPGDRPRISRQVALYLLSQVFLTIHYAPLVNCLADVILNGDLSVF--------SSKAEHDAQRS 355

  Fly   383 -REVVVPGFGEPDESLEQALDT-------------------VTGQSSSSSYALSED----SGVES 423
             .|..:..|.:|.|:||::|:.                   ...:....|..:|||    .|.||
 Frog   356 SGEASIRCFIKPQETLEKSLEINRQRGKKKLQKRPNYKNVGEEEEEDKGSEEISEDPDKAKGAES 420

  Fly   424 SSPAT-----TE-----LDSQADAVEAEQIKLRNITDEEKQLLQKSSSSTKADFAEMAKPFLDTV 478
            ||..|     ||     :..::.:.|...:...|.|||||......:.|.:      .:||||.|
 Frog   421 SSKGTKASGETEEIEMVIMERSKSSEKSAVTEENTTDEEKSAAASGTESCQ------NRPFLDMV 479

  Fly   479 LHALDCTENDYLALLSLCLIYAMSHNRGIKNEWFE--QVLAKSTRGAFSYKTALIEHLLNIITQS 541
            ...|:|||:||..|..|||:|||:||.||.....|  |:..:.::...:|...|.|.|:.|::|:
 Frog   480 YSTLECTEDDYYTLFVLCLLYAMTHNTGINPSKLERIQLSLQPSQENRTYNHVLAERLIRIMSQA 544

  Fly   542 SQPSSRIRLITVEIALELLVTFTRPSSDDSRCITAAQQDL----LFSARNQSMVVIRNFYKSEDI 602
            :|..|::||.|:|:...||....   .:||.||.   :|:    |..||.:|:.::|:|||.|:|
 Frog   545 AQTDSKVRLATLELTCILLKHLV---LNDSGCII---KDVHLACLEGAREESVHLLRHFYKGEEI 603

  Fly   603 FLDLFEDEYNEMRKAQLNVEFLCMDSTILLPPTGTPLTGINFTRRLPCGEVEKARRAIRVYFLLR 667
            |||:|||||..|....||||:|.||.:|||||||||||||:|.:|||||:||:.||||||:|:||
 Frog   604 FLDMFEDEYRSMTSKPLNVEYLMMDESILLPPTGTPLTGIDFVKRLPCGDVERTRRAIRVFFMLR 668

  Fly   668 RTCQKFLNEKESLLPLTNVVNLVQVENVLDL-------------------------------NNS 701
            ....:...|.|:.||||...:|:::::||||                               |||
 Frog   669 SLSLQLRKELETQLPLTREEDLIKMDDVLDLTLNFKKNVRAWGSPDDEDSSQDVMEFALAGQNNS 733

  Fly   702 DLIACTVVAKDSSKQRRFLVIDALQLILVEPDAKLLGWGVAKFVGFLQDVEVQGDKDDSRCLHIT 766
            |||||:|:.||..:.:|||.:|..|:.|||||:|.|||||.||.|.|||::|.|.:||||.|:||
 Frog   734 DLIACSVLTKDGGQVQRFLAVDIYQMSLVEPDSKRLGWGVVKFAGLLQDMQVTGVEDDSRALNIT 798

  Fly   767 VHRGGVT-HNRT-PLLSAKFLFDDHIRCMAAKQRLTKGRSKARQKKMYQIAQLIEIPGQMDSPVY 829
            :|:...| |::. |:|.|.|:|.|||||:.|||||.|||.:||:.||.:|:.|:::|.|..:.|.
 Frog   799 IHKPASTPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRISALLDLPVQPSTEVM 863

  Fly   830 AVGGTMVASSSGGS-------GNSSGSSSRSSHHRPMFSTANRVPGFAAVLRGSNSAGVSRTQMA 887
            ..|    .|||...       ..|..:.|..:..||.|.:.::|||| ||.:..|....|... :
 Frog   864 GFG----HSSSAAQHLPFRFYEQSRRALSDLTMQRPGFGSVDKVPGF-AVAQCINQHSTSPAS-S 922

  Fly   888 PNRSIEGIRNESAG------RSRRRSPSST-SGSNLRADHSD-----RERSPSVSMGSHSSSQSR 940
            |:....|..:.|.|      .|...:||:. |.|.|.....|     |.::.:...|...||.|.
 Frog   923 PSPPSSGSSSGSTGVCDSVTTSLTSTPSTLHSPSGLAGKEDDECLVYRRQTVTADTGFRPSSGSC 987

  Fly   941 EN---SQPRSTGNRSRESSPR----MPRPRSEEIPLEDFQHSRNNSPHSRGNPSPASRSHTPIRV 998
            .|   .||:.|.....|::..    :.:.|:.         |.|.|...:.|.:|   |.||
 Frog   988 LNDASDQPQLTTCNQEETADEHQAAVSKARTS---------SLNKSDTEKTNLAP---SLTP--- 1037

  Fly   999 LHYDQLSGHSGSPREASLGGTNALLSQLNG--LNRE------------------VLPTQSSEETS 1043
                       :|:.     |.:|:|..||  |:.|                  :|...:..|||
 Frog  1038 -----------APQP-----TISLISDENGDALSVESLTLVPPVDPQSIHAISSILQAHTESETS 1086

  Fly  1044 FIGSDGNEATGG 1055
               |:..:::||
 Frog  1087 ---SENEDSSGG 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ema	NP_650542.1	FPL	50..199	CDD:313053	117/148 (79%)
clec16a	XP_004918003.1	FPL	50..197	CDD:286801	117/148 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	525	1.000	Domainoid score	I300
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H71019
Inparanoid	1	1.050	814	1.000	Inparanoid score	I469
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1319544at2759
OrthoFinder	1	1.000	-	-		FOG0006421
OrthoInspector	1	1.000	-	-		oto105608
Panther	1	1.100	-	-	LDO	PTHR21481
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5071
SonicParanoid	1	1.000	-	-		X4687
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.190