DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17565 and Pggt1b

DIOPT Version :9

Sequence 1:	NP_650540.1	Gene:	CG17565 / 41989	FlyBaseID:	FBgn0038424	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_112344.1	Gene:	Pggt1b / 81746	RGDID:	621754	Length:	377	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	101/383 - (26%)
Similarity:	162/383 - (42%)	Gaps:	82/383 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 DPRLT--------QIFRLEHQYYLDAMLRRLPSNYECLDSSRAWCVYWILQAAQLLS----FNFD 106
            |.||.        ...|..|..:....|:.||..|..|::||....::.|....:|.    .|.|
  Rat     6 DDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKD 70

  Fly   107 DQTLNHVVQFLSNCR-SPTG--------GFGGG-----------------PGQYAHLAPTYAAVN 145
            |     :::::.:.: .||.        ||.|.                 |....|:|.||..::
  Rat    71 D-----IIEWIYSLQVLPTEDRSNLDRCGFRGSSYLGIPFNPSKNPGTAHPYDSGHIAMTYTGLS 130

  Fly   146 SLCIIGSEQAYRAIDRPTLVQFLFSVRDSDGSFRLHVDG-ETDVRGAYCA-ISCAKLLNLPEPVI 208
            .|.|:|.:.:  .:|:...:..|.:::..||||....:| |.|:|..||| ..|..|.|.....:
  Rat   131 CLIILGDDLS--RVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDM 193

  Fly   209 KELFAGTGDWIAQCQTYEGGFGGAPGLEAHGGYTFCGIAGLALLNEADKC----DRQALLKWTLR 269
            |:..:    :|.:..:|:.|.....|||:|||.||||||.|.|:.:.::.    :...:.:|.:.
  Rat   194 KKAIS----YIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIM 254

  Fly   270 RQMTYEGGFQGRTNKLVDGCYSFWVGATIPITQATLSGVDKQMEHTLFDVEALQEYILLCCQKQS 334
            ||   :.|:.||.||.||.|||||||||:.:.        |..::|.|  |..:.|||....:..
  Rat   255 RQ---QNGYHGRPNKPVDTCYSFWVGATLKLL--------KIFQYTNF--EKNRNYILSTQDRLV 306

  Fly   335 GGLIDKPGKPQDLYHTCYTLSGVSIAQHSECASSPQVLGDTINELLPTHPLFNIPPKS 392
            ||....|....|..|..:.:.|:|:.:.|              .:...||..|:..::
  Rat   307 GGFAKWPDSHPDALHAYFGICGLSLMEES--------------GICKVHPALNVSTRT 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17565	NP_650540.1	PLN02710	27..403	CDD:215380	101/383 (26%)
CG17565	NP_650540.1	FTase	62..360	CDD:239223	94/333 (28%)
Pggt1b	NP_112344.1	GGTase-I	22..332	CDD:239225	94/333 (28%)
		PFTB 1. /evidence=ECO:0000255	144..186		13/41 (32%)
		PFTB 2. /evidence=ECO:0000255	193..234		18/44 (41%)
		Geranylgeranyl diphosphate binding. /evidence=ECO:0000269\|PubMed:14609943, ECO:0007744\|PDB:1N4P	219..221		1/1 (100%)
		PFTB 3. /evidence=ECO:0000255	245..284		19/49 (39%)
		Geranylgeranyl diphosphate binding. /evidence=ECO:0000269\|PubMed:14609943, ECO:0007744\|PDB:1N4P	263..266		1/2 (50%)
		Geranylgeranyl diphosphate binding. /evidence=ECO:0000269\|PubMed:14609943, ECO:0007744\|PDB:1N4P	272..275		2/2 (100%)
		PFTB 4. /evidence=ECO:0000255	291..333		12/43 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820