Protein Alignment Fntb and RABGGTB

DIOPT Version :10

• Sequence 1: NP_650540.1
• Gene: Fntb / 41989
• FlyBaseID: FBgn0038424
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_004573.2
• Gene: RABGGTB / 5876
• HGNCID: 9796
• Length: 331
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 86/299 - (28%)
• Similarity: 144/299 - (48%)
• Gaps: 32/299 - (10%)

  Fly    91 VYWILQAAQLLSFNFDDQTLNHVVQFLSNCRSPTGGFGGGPGQYAHLAPTYAAVNSLCIIGSEQA 155
            :||.|....|:. .........::.|:.:|:...||.....|...||..|.:||..|.:..|
Human    50 IYWGLTVMDLMG-QLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDS--- 110

  Fly   156 YRAIDRPTLVQFLFSVRDSDGSFRLHVDGETDVRGAYCAISCAKLLNLPEPVIKELFAGTGDWIA 220
            ...||...:|:::..::..||||...:.||.|.|.::||::...||...:.:..|...   :::.
Human   111 INVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAI---EFVL 172

  Fly   221 QCQTYEGGFGGAPGLEAHGGYTFCGIAGLALLNEADKCDRQALLKWTLRRQMTYEGGFQGRTNKL 285
            .|..::||||..||.|:|.|..:|....||:.::..:.:...|..|...||:. .||..||..||
Human   173 SCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLP-SGGLNGRPEKL 236

  Fly   286 VDGCYSFWVGATIPITQATLSGVDKQMEHTLFDVEALQEYILLCCQKQSGGLIDKPGKPQDLYHT 350
            .|.|||:||.|::.|. ..|..:|:         |.|:.:||.|..:::||..|:||...|.:||
Human   237 PDVCYSWWVLASLKII-GRLHWIDR---------EKLRNFILACQDEETGGFADRPGDMVDPFHT 291

  Fly   351 CYTLSGVSIAQHSECASSPQVLGDTINELLPTHPLFNIP 389
            .:.::|:|:            ||:  .::.|.:|:|.:|
Human   292 LFGIAGLSL------------LGE--EQIKPVNPVFCMP 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fntb	NP_650540.1	FTase	62..360	CDD:239223	80/268 (30%)
RABGGTB	NP_004573.2	GGTase-II	18..301	CDD:239224	80/280 (29%)
		PFTB 1	20..61		4/10 (40%)
		PFTB 2	68..109		11/40 (28%)
		PFTB 3	116..157		12/40 (30%)
		PFTB 4	164..205		14/43 (33%)
		PFTB 5	212..253		18/42 (43%)
		PFTB 6	260..302		15/62 (24%)